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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EDF1 All Species: 52.73
Human Site: T91 Identified Species: 82.86
UniProt: O60869 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60869 NP_003783.1 148 16369 T91 G R Q S K G L T Q K D L A T K
Chimpanzee Pan troglodytes XP_001163031 156 17448 T99 G R Q S K G L T Q K D L A T K
Rhesus Macaque Macaca mulatta XP_001106825 148 16426 T91 G R Q S K G L T Q K D L A T K
Dog Lupus familis XP_537793 190 20933 T133 G R Q S K G L T Q K D L A T K
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus P69736 148 16350 T91 G R Q S K G L T Q K D L A T K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510092 151 16669 T94 G R Q G K G L T Q K D L A T K
Chicken Gallus gallus Q5ZMC0 148 16345 T91 G R Q S K G M T Q K D L A T K
Frog Xenopus laevis Q6GPQ6 147 16302 T91 G R Q G K G M T Q K D L A T K
Zebra Danio Brachydanio rerio Q6PBY3 146 16056 T90 G R Q N K G L T Q K D L A T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524110 145 16038 R111 V T D Y E A G R G I P N N L I
Honey Bee Apis mellifera XP_623269 147 16256 S90 G R Q S K G L S Q K D L A T K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788121 145 16195 T90 G R Q D K N L T Q K E L A T K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXT3 142 15563 T97 A R G E K K L T Q S Q L A H L
Baker's Yeast Sacchar. cerevisiae O14467 151 16385 S95 A R T D K K M S Q K D L A T K
Red Bread Mold Neurospora crassa Q871W6 160 17161 T103 M I G D K A M T Q K E L A T R
Conservation
Percent
Protein Identity: 100 82.6 94.5 77.8 N.A. N.A. 98.6 N.A. 87.4 93.2 88.5 82.4 N.A. 63.5 64.8 N.A. 65.5
Protein Similarity: 100 87.8 97.3 77.8 N.A. N.A. 100 N.A. 91.3 97.3 95.2 90.5 N.A. 79.7 77.6 N.A. 83.7
P-Site Identity: 100 100 100 100 N.A. N.A. 100 N.A. 93.3 93.3 86.6 93.3 N.A. 0 93.3 N.A. 80
P-Site Similarity: 100 100 100 100 N.A. N.A. 100 N.A. 93.3 100 93.3 100 N.A. 6.6 100 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. 52 41.7 36.8
Protein Similarity: N.A. N.A. N.A. 64.8 63.5 53.7
P-Site Identity: N.A. N.A. N.A. 46.6 60 46.6
P-Site Similarity: N.A. N.A. N.A. 46.6 73.3 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 0 0 14 0 0 0 0 0 0 94 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 20 0 0 0 0 0 0 74 0 0 0 0 % D
% Glu: 0 0 0 7 7 0 0 0 0 0 14 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 74 0 14 14 0 67 7 0 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 7 0 0 0 0 7 % I
% Lys: 0 0 0 0 94 14 0 0 0 87 0 0 0 0 80 % K
% Leu: 0 0 0 0 0 0 67 0 0 0 0 94 0 7 7 % L
% Met: 7 0 0 0 0 0 27 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 7 0 0 0 0 0 7 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % P
% Gln: 0 0 74 0 0 0 0 0 94 0 7 0 0 0 0 % Q
% Arg: 0 87 0 0 0 0 0 7 0 0 0 0 0 0 7 % R
% Ser: 0 0 0 47 0 0 0 14 0 7 0 0 0 0 0 % S
% Thr: 0 7 7 0 0 0 0 80 0 0 0 0 0 87 0 % T
% Val: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _