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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDF1
All Species:
27.88
Human Site:
S87
Identified Species:
43.81
UniProt:
O60869
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60869
NP_003783.1
148
16369
S87
V
I
Q
Q
G
R
Q
S
K
G
L
T
Q
K
D
Chimpanzee
Pan troglodytes
XP_001163031
156
17448
S95
V
I
Q
Q
G
R
Q
S
K
G
L
T
Q
K
D
Rhesus Macaque
Macaca mulatta
XP_001106825
148
16426
S87
V
I
Q
Q
G
R
Q
S
K
G
L
T
Q
K
D
Dog
Lupus familis
XP_537793
190
20933
S129
V
I
Q
Q
G
R
Q
S
K
G
L
T
Q
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P69736
148
16350
S87
V
I
Q
R
G
R
Q
S
K
G
L
T
Q
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510092
151
16669
G90
V
I
Q
Q
G
R
Q
G
K
G
L
T
Q
K
D
Chicken
Gallus gallus
Q5ZMC0
148
16345
S87
V
I
Q
Q
G
R
Q
S
K
G
M
T
Q
K
D
Frog
Xenopus laevis
Q6GPQ6
147
16302
G87
V
I
Q
Q
G
R
Q
G
K
G
M
T
Q
K
D
Zebra Danio
Brachydanio rerio
Q6PBY3
146
16056
N86
V
I
Q
Q
G
R
Q
N
K
G
L
T
Q
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524110
145
16038
Y107
K
Q
Q
V
V
T
D
Y
E
A
G
R
G
I
P
Honey Bee
Apis mellifera
XP_623269
147
16256
S86
L
I
Q
Q
G
R
Q
S
K
G
L
S
Q
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788121
145
16195
D86
V
M
Q
R
G
R
Q
D
K
N
L
T
Q
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXT3
142
15563
E93
A
I
M
Q
A
R
G
E
K
K
L
T
Q
S
Q
Baker's Yeast
Sacchar. cerevisiae
O14467
151
16385
D91
A
I
S
R
A
R
T
D
K
K
M
S
Q
K
D
Red Bread Mold
Neurospora crassa
Q871W6
160
17161
D99
R
S
A
I
M
I
G
D
K
A
M
T
Q
K
E
Conservation
Percent
Protein Identity:
100
82.6
94.5
77.8
N.A.
N.A.
98.6
N.A.
87.4
93.2
88.5
82.4
N.A.
63.5
64.8
N.A.
65.5
Protein Similarity:
100
87.8
97.3
77.8
N.A.
N.A.
100
N.A.
91.3
97.3
95.2
90.5
N.A.
79.7
77.6
N.A.
83.7
P-Site Identity:
100
100
100
100
N.A.
N.A.
93.3
N.A.
93.3
93.3
86.6
93.3
N.A.
6.6
86.6
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
N.A.
100
N.A.
93.3
100
93.3
100
N.A.
13.3
100
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
52
41.7
36.8
Protein Similarity:
N.A.
N.A.
N.A.
64.8
63.5
53.7
P-Site Identity:
N.A.
N.A.
N.A.
46.6
40
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
60
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
7
0
14
0
0
0
0
14
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
20
0
0
0
0
0
0
74
% D
% Glu:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
74
0
14
14
0
67
7
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
80
0
7
0
7
0
0
0
0
0
0
0
7
0
% I
% Lys:
7
0
0
0
0
0
0
0
94
14
0
0
0
87
0
% K
% Leu:
7
0
0
0
0
0
0
0
0
0
67
0
0
0
0
% L
% Met:
0
7
7
0
7
0
0
0
0
0
27
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
7
80
67
0
0
74
0
0
0
0
0
94
0
7
% Q
% Arg:
7
0
0
20
0
87
0
0
0
0
0
7
0
0
0
% R
% Ser:
0
7
7
0
0
0
0
47
0
0
0
14
0
7
0
% S
% Thr:
0
0
0
0
0
7
7
0
0
0
0
80
0
0
0
% T
% Val:
67
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _