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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDF1
All Species:
30.91
Human Site:
S53
Identified Species:
48.57
UniProt:
O60869
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60869
NP_003783.1
148
16369
S53
A
G
Q
N
K
Q
H
S
I
T
K
N
T
A
K
Chimpanzee
Pan troglodytes
XP_001163031
156
17448
S61
A
G
Q
N
K
Q
H
S
I
T
K
N
T
A
K
Rhesus Macaque
Macaca mulatta
XP_001106825
148
16426
S53
A
G
Q
N
K
Q
H
S
I
T
K
N
T
A
K
Dog
Lupus familis
XP_537793
190
20933
S95
A
G
Q
N
K
Q
H
S
I
T
K
N
T
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P69736
148
16350
S53
A
G
Q
N
K
Q
H
S
I
T
K
N
T
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510092
151
16669
S56
A
G
Q
N
K
Q
H
S
I
T
K
N
T
A
K
Chicken
Gallus gallus
Q5ZMC0
148
16345
F53
A
G
Q
N
K
Q
H
F
I
T
K
N
T
A
K
Frog
Xenopus laevis
Q6GPQ6
147
16302
T53
A
G
Q
N
K
Q
H
T
I
T
R
N
T
A
K
Zebra Danio
Brachydanio rerio
Q6PBY3
146
16056
V52
A
G
Q
N
K
Q
H
V
V
T
K
N
T
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524110
145
16038
L73
L
R
H
D
K
I
P
L
D
V
G
K
L
I
Q
Honey Bee
Apis mellifera
XP_623269
147
16256
V52
G
G
T
N
K
Q
H
V
A
T
K
N
T
A
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788121
145
16195
S52
A
G
T
N
K
Q
K
S
A
S
K
N
T
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXT3
142
15563
G59
S
N
K
A
A
S
S
G
T
S
L
N
T
K
K
Baker's Yeast
Sacchar. cerevisiae
O14467
151
16385
N57
S
T
N
T
R
G
D
N
E
G
Q
R
L
T
K
Red Bread Mold
Neurospora crassa
Q871W6
160
17161
L65
P
G
V
E
G
Q
R
L
T
M
V
D
R
S
D
Conservation
Percent
Protein Identity:
100
82.6
94.5
77.8
N.A.
N.A.
98.6
N.A.
87.4
93.2
88.5
82.4
N.A.
63.5
64.8
N.A.
65.5
Protein Similarity:
100
87.8
97.3
77.8
N.A.
N.A.
100
N.A.
91.3
97.3
95.2
90.5
N.A.
79.7
77.6
N.A.
83.7
P-Site Identity:
100
100
100
100
N.A.
N.A.
100
N.A.
100
93.3
86.6
86.6
N.A.
6.6
73.3
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
N.A.
100
N.A.
100
93.3
100
93.3
N.A.
20
73.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
52
41.7
36.8
Protein Similarity:
N.A.
N.A.
N.A.
64.8
63.5
53.7
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
0
7
7
0
0
0
14
0
0
0
0
74
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
7
0
7
0
0
7
0
0
7
% D
% Glu:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
7
80
0
0
7
7
0
7
0
7
7
0
0
0
0
% G
% His:
0
0
7
0
0
0
67
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
54
0
0
0
0
7
0
% I
% Lys:
0
0
7
0
80
0
7
0
0
0
67
7
0
7
87
% K
% Leu:
7
0
0
0
0
0
0
14
0
0
7
0
14
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
7
7
74
0
0
0
7
0
0
0
80
0
0
0
% N
% Pro:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
60
0
0
80
0
0
0
0
7
0
0
0
7
% Q
% Arg:
0
7
0
0
7
0
7
0
0
0
7
7
7
0
0
% R
% Ser:
14
0
0
0
0
7
7
47
0
14
0
0
0
7
0
% S
% Thr:
0
7
14
7
0
0
0
7
14
67
0
0
80
7
0
% T
% Val:
0
0
7
0
0
0
0
14
7
7
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _