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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDF1
All Species:
26.97
Human Site:
S24
Identified Species:
42.38
UniProt:
O60869
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60869
NP_003783.1
148
16369
S24
P
T
A
A
Q
A
K
S
K
Q
A
I
L
A
A
Chimpanzee
Pan troglodytes
XP_001163031
156
17448
A32
A
T
Y
W
A
C
R
A
R
E
A
I
L
A
A
Rhesus Macaque
Macaca mulatta
XP_001106825
148
16426
S24
P
M
A
A
Q
A
K
S
K
Q
A
T
L
A
A
Dog
Lupus familis
XP_537793
190
20933
S66
P
T
A
A
Q
A
K
S
K
Q
A
I
L
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P69736
148
16350
S24
P
T
A
A
Q
A
K
S
K
Q
A
I
L
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510092
151
16669
R24
X
X
X
P
C
P
A
R
A
W
E
S
E
A
I
Chicken
Gallus gallus
Q5ZMC0
148
16345
S24
P
S
A
A
Q
A
K
S
K
Q
A
V
L
A
A
Frog
Xenopus laevis
Q6GPQ6
147
16302
S24
P
T
A
A
Q
A
K
S
K
Q
A
I
T
A
A
Zebra Danio
Brachydanio rerio
Q6PBY3
146
16056
K24
S
A
A
Q
S
K
S
K
Q
A
V
T
A
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524110
145
16038
S24
S
S
T
L
K
T
E
S
A
V
N
Q
A
R
R
Honey Bee
Apis mellifera
XP_623269
147
16256
E24
K
A
S
V
L
K
S
E
Q
A
V
N
A
A
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788121
145
16195
S24
S
S
K
Q
A
R
S
S
K
A
V
N
S
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXT3
142
15563
D28
P
N
A
A
A
K
R
D
E
K
T
V
N
A
A
Baker's Yeast
Sacchar. cerevisiae
O14467
151
16385
S28
P
R
A
N
V
A
R
S
Q
G
Q
I
N
A
A
Red Bread Mold
Neurospora crassa
Q871W6
160
17161
E24
R
G
G
A
G
P
R
E
T
V
V
R
G
K
S
Conservation
Percent
Protein Identity:
100
82.6
94.5
77.8
N.A.
N.A.
98.6
N.A.
87.4
93.2
88.5
82.4
N.A.
63.5
64.8
N.A.
65.5
Protein Similarity:
100
87.8
97.3
77.8
N.A.
N.A.
100
N.A.
91.3
97.3
95.2
90.5
N.A.
79.7
77.6
N.A.
83.7
P-Site Identity:
100
40
86.6
100
N.A.
N.A.
100
N.A.
6.6
86.6
93.3
13.3
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
66.6
86.6
100
N.A.
N.A.
100
N.A.
6.6
100
93.3
20
N.A.
26.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
52
41.7
36.8
Protein Similarity:
N.A.
N.A.
N.A.
64.8
63.5
53.7
P-Site Identity:
N.A.
N.A.
N.A.
33.3
46.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
60
60
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
14
60
54
20
47
7
7
14
20
47
0
20
87
60
% A
% Cys:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
7
14
7
7
7
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
7
0
0
0
0
7
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
40
0
0
7
% I
% Lys:
7
0
7
0
7
20
40
7
47
7
0
0
0
7
0
% K
% Leu:
0
0
0
7
7
0
0
0
0
0
0
0
40
0
7
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
7
0
0
0
0
0
0
7
14
14
0
0
% N
% Pro:
54
0
0
7
0
14
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
14
40
0
0
0
20
40
7
7
0
0
7
% Q
% Arg:
7
7
0
0
0
7
27
7
7
0
0
7
0
7
14
% R
% Ser:
20
20
7
0
7
0
20
60
0
0
0
7
7
0
7
% S
% Thr:
0
34
7
0
0
7
0
0
7
0
7
14
7
0
0
% T
% Val:
0
0
0
7
7
0
0
0
0
14
27
14
0
0
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _