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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC22
All Species:
18.18
Human Site:
S527
Identified Species:
33.33
UniProt:
O60826
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60826
NP_054727.1
627
70756
S527
E
L
Q
K
E
I
N
S
L
S
G
K
L
D
R
Chimpanzee
Pan troglodytes
XP_001143086
331
38131
D244
D
R
T
F
A
V
T
D
E
L
V
F
K
D
A
Rhesus Macaque
Macaca mulatta
XP_001106217
627
70698
S527
E
L
Q
K
E
I
N
S
L
S
G
K
L
D
R
Dog
Lupus familis
XP_548995
627
70779
S527
E
L
Q
K
E
I
N
S
L
S
G
K
L
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIG7
627
70825
S527
E
L
Q
K
E
I
N
S
L
S
G
K
L
D
R
Rat
Rattus norvegicus
P86182
627
70836
S527
E
L
Q
K
E
I
N
S
L
S
G
K
L
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PA15
632
72232
N532
E
L
Q
K
E
I
N
N
L
T
G
K
V
D
R
Zebra Danio
Brachydanio rerio
Q4V909
639
71968
G539
D
L
Q
K
E
I
N
G
L
T
G
K
L
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVB4
555
62995
A468
D
D
L
L
F
Q
S
A
K
H
D
L
H
A
K
Honey Bee
Apis mellifera
XP_395711
557
64268
L470
S
F
T
V
A
D
E
L
I
F
R
D
A
R
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795944
639
73126
Q539
T
L
Q
K
E
I
N
Q
V
S
G
K
L
D
R
Poplar Tree
Populus trichocarpa
XP_002298881
518
58714
L431
L
H
R
T
Y
A
V
L
D
E
I
V
C
R
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175979
412
47939
H325
N
S
I
Q
E
R
L
H
R
S
Y
A
V
V
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.7
98.4
91.5
N.A.
88
87.7
N.A.
N.A.
N.A.
53.6
56.3
N.A.
30.9
33.4
N.A.
44.2
Protein Similarity:
100
52.7
98.7
95
N.A.
92
92.1
N.A.
N.A.
N.A.
69.9
73.2
N.A.
48.1
56.9
N.A.
62.4
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
N.A.
80
80
N.A.
0
0
N.A.
80
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
N.A.
100
93.3
N.A.
26.6
6.6
N.A.
86.6
Percent
Protein Identity:
26.9
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
43.8
N.A.
N.A.
39.8
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
8
0
8
0
0
0
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
24
8
0
0
0
8
0
8
8
0
8
8
0
70
8
% D
% Glu:
47
0
0
0
70
0
8
0
8
8
0
0
0
0
8
% E
% Phe:
0
8
0
8
8
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
62
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
8
0
8
0
0
8
0
0
% H
% Ile:
0
0
8
0
0
62
0
0
8
0
8
0
0
0
0
% I
% Lys:
0
0
0
62
0
0
0
0
8
0
0
62
8
0
8
% K
% Leu:
8
62
8
8
0
0
8
16
54
8
0
8
54
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
62
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
62
8
0
8
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
8
8
0
0
8
0
0
8
0
8
0
0
16
62
% R
% Ser:
8
8
0
0
0
0
8
39
0
54
0
0
0
0
0
% S
% Thr:
8
0
16
8
0
0
8
0
0
16
0
0
0
0
8
% T
% Val:
0
0
0
8
0
8
8
0
8
0
8
8
16
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _