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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC22
All Species:
19.39
Human Site:
S459
Identified Species:
35.56
UniProt:
O60826
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60826
NP_054727.1
627
70756
S459
E
I
Q
E
L
H
Q
S
V
R
A
A
A
E
E
Chimpanzee
Pan troglodytes
XP_001143086
331
38131
K179
R
R
K
E
E
V
Y
K
Q
L
M
S
E
L
E
Rhesus Macaque
Macaca mulatta
XP_001106217
627
70698
S459
E
I
Q
E
L
H
Q
S
V
R
A
A
A
E
E
Dog
Lupus familis
XP_548995
627
70779
S459
E
I
Q
E
L
H
Q
S
V
R
A
A
A
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIG7
627
70825
S459
E
I
Q
E
L
H
H
S
V
R
A
A
A
E
E
Rat
Rattus norvegicus
P86182
627
70836
S459
E
I
Q
E
L
H
Q
S
V
R
A
A
A
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PA15
632
72232
K464
D
A
K
D
L
Y
E
K
I
Q
G
S
A
D
E
Zebra Danio
Brachydanio rerio
Q4V909
639
71968
K471
E
I
K
D
L
H
D
K
I
R
Q
S
A
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVB4
555
62995
S403
E
L
N
A
T
L
R
S
A
S
Q
S
L
A
P
Honey Bee
Apis mellifera
XP_395711
557
64268
L405
K
D
Q
Q
Y
S
Q
L
V
T
E
V
Q
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795944
639
73126
K471
D
I
Q
A
L
R
E
K
M
K
K
V
A
E
E
Poplar Tree
Populus trichocarpa
XP_002298881
518
58714
H366
I
T
K
R
E
E
E
H
S
K
L
S
A
D
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175979
412
47939
Q260
Q
S
L
S
S
E
I
Q
K
R
E
D
E
R
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.7
98.4
91.5
N.A.
88
87.7
N.A.
N.A.
N.A.
53.6
56.3
N.A.
30.9
33.4
N.A.
44.2
Protein Similarity:
100
52.7
98.7
95
N.A.
92
92.1
N.A.
N.A.
N.A.
69.9
73.2
N.A.
48.1
56.9
N.A.
62.4
P-Site Identity:
100
13.3
100
100
N.A.
93.3
100
N.A.
N.A.
N.A.
20
53.3
N.A.
13.3
20
N.A.
40
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
100
N.A.
N.A.
N.A.
80
80
N.A.
33.3
40
N.A.
66.6
Percent
Protein Identity:
26.9
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
43.8
N.A.
N.A.
39.8
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
16
0
0
0
0
8
0
39
39
70
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
16
8
0
16
0
0
8
0
0
0
0
8
0
16
0
% D
% Glu:
54
0
0
47
16
16
24
0
0
0
16
0
16
54
70
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
47
8
8
0
0
0
0
0
0
0
% H
% Ile:
8
54
0
0
0
0
8
0
16
0
0
0
0
0
0
% I
% Lys:
8
0
31
0
0
0
0
31
8
16
8
0
0
8
0
% K
% Leu:
0
8
8
0
62
8
0
8
0
8
8
0
8
8
16
% L
% Met:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
8
0
54
8
0
0
39
8
8
8
16
0
8
0
0
% Q
% Arg:
8
8
0
8
0
8
8
0
0
54
0
0
0
8
0
% R
% Ser:
0
8
0
8
8
8
0
47
8
8
0
39
0
0
0
% S
% Thr:
0
8
0
0
8
0
0
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
47
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _