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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC22
All Species:
20.91
Human Site:
S336
Identified Species:
38.33
UniProt:
O60826
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60826
NP_054727.1
627
70756
S336
A
Q
E
Q
E
L
E
S
L
R
E
Q
L
E
G
Chimpanzee
Pan troglodytes
XP_001143086
331
38131
G63
E
A
D
M
K
T
L
G
V
S
F
V
Q
A
E
Rhesus Macaque
Macaca mulatta
XP_001106217
627
70698
S336
A
Q
E
Q
E
L
E
S
L
R
E
Q
L
E
G
Dog
Lupus familis
XP_548995
627
70779
S336
A
Q
E
Q
E
L
E
S
L
R
E
Q
L
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIG7
627
70825
S336
A
Q
E
Q
E
L
E
S
L
R
E
Q
L
A
S
Rat
Rattus norvegicus
P86182
627
70836
S336
A
Q
E
E
E
L
E
S
L
R
E
Q
L
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PA15
632
72232
S341
A
E
Q
Q
E
I
S
S
L
Q
E
Q
I
D
S
Zebra Danio
Brachydanio rerio
Q4V909
639
71968
A348
Q
Q
E
A
E
L
S
A
L
Q
Q
Q
L
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVB4
555
62995
H287
L
L
A
E
R
K
A
H
A
V
A
I
A
A
L
Honey Bee
Apis mellifera
XP_395711
557
64268
K289
D
L
Q
I
E
K
I
K
T
E
C
E
T
I
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795944
639
73126
D348
K
R
E
D
E
Q
T
D
L
K
E
Q
L
S
R
Poplar Tree
Populus trichocarpa
XP_002298881
518
58714
E250
K
E
E
L
R
N
E
E
K
V
L
T
E
E
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175979
412
47939
V144
F
E
T
N
Y
E
T
V
E
L
Q
N
Q
H
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.7
98.4
91.5
N.A.
88
87.7
N.A.
N.A.
N.A.
53.6
56.3
N.A.
30.9
33.4
N.A.
44.2
Protein Similarity:
100
52.7
98.7
95
N.A.
92
92.1
N.A.
N.A.
N.A.
69.9
73.2
N.A.
48.1
56.9
N.A.
62.4
P-Site Identity:
100
0
100
100
N.A.
86.6
80
N.A.
N.A.
N.A.
46.6
46.6
N.A.
0
6.6
N.A.
40
P-Site Similarity:
100
20
100
100
N.A.
86.6
86.6
N.A.
N.A.
N.A.
86.6
73.3
N.A.
6.6
20
N.A.
53.3
Percent
Protein Identity:
26.9
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
43.8
N.A.
N.A.
39.8
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
8
8
8
0
0
8
8
8
0
8
0
8
31
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
0
8
8
0
0
0
8
0
0
0
0
0
8
8
% D
% Glu:
8
24
62
16
70
8
47
8
8
8
54
8
8
31
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
24
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
8
0
8
8
0
0
0
0
8
8
8
0
% I
% Lys:
16
0
0
0
8
16
0
8
8
8
0
0
0
0
0
% K
% Leu:
8
16
0
8
0
47
8
0
62
8
8
0
54
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
47
16
39
0
8
0
0
0
16
16
62
16
8
8
% Q
% Arg:
0
8
0
0
16
0
0
0
0
39
0
0
0
0
16
% R
% Ser:
0
0
0
0
0
0
16
47
0
8
0
0
0
8
24
% S
% Thr:
0
0
8
0
0
8
16
0
8
0
0
8
8
0
0
% T
% Val:
0
0
0
0
0
0
0
8
8
16
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _