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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC22
All Species:
18.18
Human Site:
S319
Identified Species:
33.33
UniProt:
O60826
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60826
NP_054727.1
627
70756
S319
V
S
D
V
P
A
T
S
R
R
P
E
Q
V
T
Chimpanzee
Pan troglodytes
XP_001143086
331
38131
E46
E
S
L
R
E
Q
L
E
G
V
N
R
S
I
E
Rhesus Macaque
Macaca mulatta
XP_001106217
627
70698
S319
V
S
D
V
P
A
T
S
R
R
P
E
Q
D
T
Dog
Lupus familis
XP_548995
627
70779
S319
V
S
D
M
P
V
T
S
Q
Q
P
E
Q
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIG7
627
70825
S319
V
A
D
V
P
A
T
S
Q
R
L
E
Q
D
T
Rat
Rattus norvegicus
P86182
627
70836
S319
V
A
D
I
P
A
A
S
Q
R
P
E
Q
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PA15
632
72232
L324
M
Q
R
A
A
E
I
L
P
K
K
D
A
Q
D
Zebra Danio
Brachydanio rerio
Q4V909
639
71968
S331
A
A
S
A
L
P
S
S
Q
Q
S
E
E
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVB4
555
62995
V270
I
Q
E
L
S
D
Q
V
Q
E
L
R
V
Q
C
Honey Bee
Apis mellifera
XP_395711
557
64268
Q272
K
E
I
K
L
I
K
Q
K
I
I
D
K
T
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795944
639
73126
R331
G
I
G
E
G
G
P
R
A
D
T
E
E
E
L
Poplar Tree
Populus trichocarpa
XP_002298881
518
58714
K233
V
Q
K
A
I
S
I
K
E
Q
P
S
M
V
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175979
412
47939
R127
L
S
L
R
D
S
S
R
C
E
E
N
S
Y
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.7
98.4
91.5
N.A.
88
87.7
N.A.
N.A.
N.A.
53.6
56.3
N.A.
30.9
33.4
N.A.
44.2
Protein Similarity:
100
52.7
98.7
95
N.A.
92
92.1
N.A.
N.A.
N.A.
69.9
73.2
N.A.
48.1
56.9
N.A.
62.4
P-Site Identity:
100
6.6
93.3
66.6
N.A.
73.3
66.6
N.A.
N.A.
N.A.
0
13.3
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
13.3
93.3
86.6
N.A.
86.6
86.6
N.A.
N.A.
N.A.
20
46.6
N.A.
26.6
20
N.A.
13.3
Percent
Protein Identity:
26.9
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
43.8
N.A.
N.A.
39.8
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
0
24
8
31
8
0
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% C
% Asp:
0
0
39
0
8
8
0
0
0
8
0
16
0
39
8
% D
% Glu:
8
8
8
8
8
8
0
8
8
16
8
54
16
8
24
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
8
8
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
8
8
8
8
16
0
0
8
8
0
0
8
8
% I
% Lys:
8
0
8
8
0
0
8
8
8
8
8
0
8
0
0
% K
% Leu:
8
0
16
8
16
0
8
8
0
0
16
0
0
0
16
% L
% Met:
8
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
39
8
8
0
8
0
39
0
0
0
0
% P
% Gln:
0
24
0
0
0
8
8
8
39
24
0
0
39
16
0
% Q
% Arg:
0
0
8
16
0
0
0
16
16
31
0
16
0
0
0
% R
% Ser:
0
39
8
0
8
16
16
47
0
0
8
8
16
0
0
% S
% Thr:
0
0
0
0
0
0
31
0
0
0
8
0
0
8
39
% T
% Val:
47
0
0
24
0
8
0
8
0
8
0
0
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _