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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC22
All Species:
14.24
Human Site:
S233
Identified Species:
26.11
UniProt:
O60826
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60826
NP_054727.1
627
70756
S233
E
D
W
V
H
R
T
S
R
L
P
P
Q
E
D
Chimpanzee
Pan troglodytes
XP_001143086
331
38131
Rhesus Macaque
Macaca mulatta
XP_001106217
627
70698
S233
E
D
W
V
P
R
T
S
R
L
P
P
Q
E
D
Dog
Lupus familis
XP_548995
627
70779
P233
E
D
W
V
Q
R
A
P
R
H
P
T
Q
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIG7
627
70825
S233
E
D
R
V
R
W
A
S
R
V
P
S
Q
E
D
Rat
Rattus norvegicus
P86182
627
70836
S233
E
D
R
V
R
W
A
S
R
L
P
S
Q
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PA15
632
72232
A233
E
W
K
S
Q
G
L
A
S
R
L
S
P
E
D
Zebra Danio
Brachydanio rerio
Q4V909
639
71968
S236
W
N
S
Q
G
L
L
S
R
L
T
P
E
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVB4
555
62995
Q195
Q
Q
Q
Y
L
D
Q
Q
A
P
N
L
F
Q
Q
Honey Bee
Apis mellifera
XP_395711
557
64268
L197
M
Q
N
E
M
T
L
L
P
S
L
I
S
Y
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795944
639
73126
S241
W
N
T
T
G
L
P
S
R
L
S
Q
E
E
Y
Poplar Tree
Populus trichocarpa
XP_002298881
518
58714
Q158
G
R
L
D
L
N
H
Q
R
E
K
L
A
D
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175979
412
47939
D52
P
K
M
E
T
F
R
D
I
S
D
D
M
M
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.7
98.4
91.5
N.A.
88
87.7
N.A.
N.A.
N.A.
53.6
56.3
N.A.
30.9
33.4
N.A.
44.2
Protein Similarity:
100
52.7
98.7
95
N.A.
92
92.1
N.A.
N.A.
N.A.
69.9
73.2
N.A.
48.1
56.9
N.A.
62.4
P-Site Identity:
100
0
93.3
66.6
N.A.
60
66.6
N.A.
N.A.
N.A.
20
33.3
N.A.
0
0
N.A.
26.6
P-Site Similarity:
100
0
93.3
66.6
N.A.
66.6
66.6
N.A.
N.A.
N.A.
26.6
46.6
N.A.
13.3
6.6
N.A.
40
Percent
Protein Identity:
26.9
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
43.8
N.A.
N.A.
39.8
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
24
8
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
39
0
8
0
8
0
8
0
0
8
8
0
8
47
% D
% Glu:
47
0
0
16
0
0
0
0
0
8
0
0
16
62
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
16
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% I
% Lys:
0
8
8
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
8
0
16
16
24
8
0
39
16
16
0
0
0
% L
% Met:
8
0
8
0
8
0
0
0
0
0
0
0
8
8
0
% M
% Asn:
0
16
8
0
0
8
0
0
0
0
8
0
0
0
8
% N
% Pro:
8
0
0
0
8
0
8
8
8
8
39
24
8
0
8
% P
% Gln:
8
16
8
8
16
0
8
16
0
0
0
8
39
8
8
% Q
% Arg:
0
8
16
0
16
24
8
0
62
8
0
0
0
0
0
% R
% Ser:
0
0
8
8
0
0
0
47
8
16
8
24
8
0
0
% S
% Thr:
0
0
8
8
8
8
16
0
0
0
8
8
0
0
0
% T
% Val:
0
0
0
39
0
0
0
0
0
8
0
0
0
0
8
% V
% Trp:
16
8
24
0
0
16
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _