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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPGDS
All Species:
20.61
Human Site:
T176
Identified Species:
45.33
UniProt:
O60760
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60760
NP_055300.1
199
23344
T176
D
N
H
P
R
L
V
T
L
R
K
K
V
Q
A
Chimpanzee
Pan troglodytes
XP_001163736
199
23339
T176
D
N
H
P
R
L
V
T
L
R
K
K
V
Q
A
Rhesus Macaque
Macaca mulatta
XP_001102342
199
23301
T176
D
I
H
P
R
L
V
T
L
R
K
K
V
Q
A
Dog
Lupus familis
XP_535659
199
23424
T176
D
I
H
P
R
L
V
T
L
R
K
K
V
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHF7
199
23209
S176
D
I
Y
P
K
L
V
S
L
R
N
K
V
Q
A
Rat
Rattus norvegicus
O35543
199
23278
S176
G
I
Y
P
R
L
V
S
L
R
N
K
V
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509662
275
31194
A252
D
N
F
P
T
L
V
A
L
R
G
R
V
Q
T
Chicken
Gallus gallus
O73888
199
22712
A176
D
K
Y
P
R
L
L
A
L
R
D
R
V
E
A
Frog
Xenopus laevis
Q8JFZ2
212
24409
A181
S
A
Y
P
L
L
T
A
Y
V
E
R
L
V
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P41043
249
27595
G226
E
P
Y
P
A
L
R
G
V
V
D
A
V
N
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21743
206
23518
D183
D
T
F
L
E
M
K
D
H
Q
K
K
I
H
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.9
87.4
N.A.
80.4
81.4
N.A.
51.6
66.3
26.4
N.A.
N.A.
28.9
N.A.
34.9
N.A.
Protein Similarity:
100
100
98.9
94.4
N.A.
90.4
90.9
N.A.
60.3
83.9
44.3
N.A.
N.A.
48.1
N.A.
52.9
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
66.6
66.6
N.A.
60
53.3
20
N.A.
N.A.
26.6
N.A.
20
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
80
N.A.
66.6
80
46.6
N.A.
N.A.
46.6
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
0
28
0
0
0
10
0
0
82
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
73
0
0
0
0
0
0
10
0
0
19
0
0
0
0
% D
% Glu:
10
0
0
0
10
0
0
0
0
0
10
0
0
10
0
% E
% Phe:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% G
% His:
0
0
37
0
0
0
0
0
10
0
0
0
0
10
0
% H
% Ile:
0
37
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
10
0
0
10
0
10
0
0
0
46
64
0
0
0
% K
% Leu:
0
0
0
10
10
91
10
0
73
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
28
0
0
0
0
0
0
0
0
19
0
0
10
0
% N
% Pro:
0
10
0
91
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
64
0
% Q
% Arg:
0
0
0
0
55
0
10
0
0
73
0
28
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
19
0
0
0
0
0
0
10
% S
% Thr:
0
10
0
0
10
0
10
37
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
64
0
10
19
0
0
82
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
46
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _