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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLA2G6
All Species:
20
Human Site:
Y536
Identified Species:
55
UniProt:
O60733
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60733
NP_001004426.1
806
89903
Y536
L
H
S
K
S
M
A
Y
M
R
G
M
Y
F
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850251
836
92917
Y566
L
H
S
K
S
M
A
Y
M
R
G
V
Y
F
R
Cat
Felis silvestris
Mouse
Mus musculus
P97819
752
83684
Y482
L
H
S
K
S
M
A
Y
M
R
G
V
Y
F
R
Rat
Rattus norvegicus
P97570
751
83564
Y481
L
H
S
K
S
M
A
Y
M
R
G
V
Y
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124210
796
88378
Y527
V
H
G
K
S
M
D
Y
M
R
C
L
Y
F
R
Frog
Xenopus laevis
NP_001086854
756
84285
S486
V
H
G
M
P
M
E
S
V
R
C
L
Y
F
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394049
798
88142
E522
A
A
G
K
S
L
R
E
C
Q
A
L
Y
F
R
Nematode Worm
Caenorhab. elegans
NP_508000
1023
114506
A750
T
G
G
S
L
R
K
A
Q
R
Y
Y
L
M
F
Sea Urchin
Strong. purpuratus
XP_781913
745
81575
E474
S
Q
G
F
S
V
E
E
C
R
K
L
Y
M
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
87.5
N.A.
85.1
84.1
N.A.
N.A.
62.1
57.5
N.A.
N.A.
N.A.
36
24.5
34.3
Protein Similarity:
100
N.A.
N.A.
91
N.A.
89
88.2
N.A.
N.A.
77.6
73.9
N.A.
N.A.
N.A.
56.9
43.8
51.3
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
40
N.A.
N.A.
N.A.
33.3
6.6
20
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
80
60
N.A.
N.A.
N.A.
53.3
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
0
0
0
45
12
0
0
12
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
23
0
23
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
23
23
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
78
12
% F
% Gly:
0
12
56
0
0
0
0
0
0
0
45
0
0
0
0
% G
% His:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
67
0
0
12
0
0
0
12
0
0
0
0
% K
% Leu:
45
0
0
0
12
12
0
0
0
0
0
45
12
0
0
% L
% Met:
0
0
0
12
0
67
0
0
56
0
0
12
0
23
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
0
0
0
0
0
12
12
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
12
0
0
89
0
0
0
0
78
% R
% Ser:
12
0
45
12
78
0
0
12
0
0
0
0
0
0
0
% S
% Thr:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
23
0
0
0
0
12
0
0
12
0
0
34
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
56
0
0
12
12
89
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _