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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLA2G6 All Species: 7.88
Human Site: Y286 Identified Species: 21.67
UniProt: O60733 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60733 NP_001004426.1 806 89903 Y286 I H S K D P R Y G A S P L H W
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850251 836 92917 Y316 I H S K D P R Y G A S P L H W
Cat Felis silvestris
Mouse Mus musculus P97819 752 83684 K261 F P I H T A M K F S Q K G C A
Rat Rattus norvegicus P97570 751 83564 K260 F P I H T A M K F S Q K G C A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001124210 796 88378 H277 V H S R D P R H E A V P L H W
Frog Xenopus laevis NP_001086854 756 84285 S263 I H T A M K Y S Q K E C V E A
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394049 798 88142 F281 L H A E D M R F G G T P L H W
Nematode Worm Caenorhab. elegans NP_508000 1023 114506 T458 L T E T E P T T G N T V I H C
Sea Urchin Strong. purpuratus XP_781913 745 81575 V250 F D A A I K L V K S G A T V D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 87.5 N.A. 85.1 84.1 N.A. N.A. 62.1 57.5 N.A. N.A. N.A. 36 24.5 34.3
Protein Similarity: 100 N.A. N.A. 91 N.A. 89 88.2 N.A. N.A. 77.6 73.9 N.A. N.A. N.A. 56.9 43.8 51.3
P-Site Identity: 100 N.A. N.A. 100 N.A. 0 0 N.A. N.A. 66.6 13.3 N.A. N.A. N.A. 53.3 20 0
P-Site Similarity: 100 N.A. N.A. 100 N.A. 6.6 6.6 N.A. N.A. 86.6 26.6 N.A. N.A. N.A. 86.6 46.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 23 23 0 23 0 0 0 34 0 12 0 0 34 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 12 0 23 12 % C
% Asp: 0 12 0 0 45 0 0 0 0 0 0 0 0 0 12 % D
% Glu: 0 0 12 12 12 0 0 0 12 0 12 0 0 12 0 % E
% Phe: 34 0 0 0 0 0 0 12 23 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 45 12 12 0 23 0 0 % G
% His: 0 56 0 23 0 0 0 12 0 0 0 0 0 56 0 % H
% Ile: 34 0 23 0 12 0 0 0 0 0 0 0 12 0 0 % I
% Lys: 0 0 0 23 0 23 0 23 12 12 0 23 0 0 0 % K
% Leu: 23 0 0 0 0 0 12 0 0 0 0 0 45 0 0 % L
% Met: 0 0 0 0 12 12 23 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % N
% Pro: 0 23 0 0 0 45 0 0 0 0 0 45 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 12 0 23 0 0 0 0 % Q
% Arg: 0 0 0 12 0 0 45 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 34 0 0 0 0 12 0 34 23 0 0 0 0 % S
% Thr: 0 12 12 12 23 0 12 12 0 0 23 0 12 0 0 % T
% Val: 12 0 0 0 0 0 0 12 0 0 12 12 12 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 % W
% Tyr: 0 0 0 0 0 0 12 23 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _