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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC24A1
All Species:
4.55
Human Site:
S425
Identified Species:
10
UniProt:
O60721
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60721
NP_004718.1
1099
121374
S425
E
E
L
S
P
S
P
S
V
L
P
P
S
L
P
Chimpanzee
Pan troglodytes
XP_001174585
1096
121151
S425
E
E
L
S
P
S
P
S
V
L
P
P
S
L
P
Rhesus Macaque
Macaca mulatta
XP_001103481
812
89131
D222
T
L
R
T
T
V
K
D
S
D
I
T
T
T
Y
Dog
Lupus familis
XP_864917
651
72717
E61
F
S
I
S
A
F
S
E
P
E
T
Q
S
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99PD7
645
71896
G55
L
D
L
M
D
L
I
G
E
D
R
K
W
M
V
Rat
Rattus norvegicus
Q9QZM6
1181
129963
H425
R
Q
G
W
V
V
L
H
I
F
G
M
T
Y
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514353
346
38802
Chicken
Gallus gallus
Q9IAL8
663
73753
I73
N
V
T
A
A
P
K
I
R
H
C
V
Y
I
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q49SH1
513
56764
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U6A0
888
95868
N298
S
D
E
D
N
A
G
N
Q
R
G
I
N
D
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787540
651
70927
G61
D
G
Q
I
N
G
D
G
I
L
E
H
S
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
69.1
39.4
N.A.
26.4
67.2
N.A.
21.2
42.9
N.A.
20
N.A.
32.6
N.A.
N.A.
30.1
Protein Similarity:
100
99.2
71
47.5
N.A.
38.6
74.9
N.A.
26.6
51
N.A.
32
N.A.
47.9
N.A.
N.A.
39.6
P-Site Identity:
100
100
0
13.3
N.A.
6.6
0
N.A.
0
0
N.A.
0
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
100
13.3
20
N.A.
20
20
N.A.
0
13.3
N.A.
0
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
19
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
19
0
10
10
0
10
10
0
19
0
0
0
10
10
% D
% Glu:
19
19
10
0
0
0
0
10
10
10
10
0
0
0
10
% E
% Phe:
10
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
10
10
19
0
0
19
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
10
0
10
0
0
0
% H
% Ile:
0
0
10
10
0
0
10
10
19
0
10
10
0
10
0
% I
% Lys:
0
0
0
0
0
0
19
0
0
0
0
10
0
0
0
% K
% Leu:
10
10
28
0
0
10
10
0
0
28
0
0
0
19
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
10
0
10
0
% M
% Asn:
10
0
0
0
19
0
0
10
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
19
10
19
0
10
0
19
19
0
0
19
% P
% Gln:
0
10
10
0
0
0
0
0
10
0
0
10
0
0
0
% Q
% Arg:
10
0
10
0
0
0
0
0
10
10
10
0
0
0
10
% R
% Ser:
10
10
0
28
0
19
10
19
10
0
0
0
37
0
0
% S
% Thr:
10
0
10
10
10
0
0
0
0
0
10
10
19
19
10
% T
% Val:
0
10
0
0
10
19
0
0
19
0
0
10
0
10
19
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _