KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY9
All Species:
16.36
Human Site:
T623
Identified Species:
30
UniProt:
O60503
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60503
NP_001107.2
1353
150701
T623
D
L
A
Q
T
V
K
T
F
D
N
L
K
T
C
Chimpanzee
Pan troglodytes
XP_510775
1356
150504
T623
D
L
A
Q
T
V
K
T
F
D
N
L
K
T
C
Rhesus Macaque
Macaca mulatta
XP_001095164
805
89192
S143
K
L
T
N
S
Q
T
S
L
C
E
I
L
Q
E
Dog
Lupus familis
XP_547151
1352
150601
T623
D
L
A
Q
T
V
K
T
F
D
N
L
K
T
C
Cat
Felis silvestris
Mouse
Mus musculus
P51830
1353
150936
T623
D
L
A
Q
T
V
K
T
F
D
N
L
K
T
C
Rat
Rattus norvegicus
P26769
1090
123297
S428
P
G
R
V
H
I
S
S
V
T
L
E
H
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511444
787
88031
T125
E
K
L
T
N
S
Q
T
S
L
Y
E
M
L
Q
Chicken
Gallus gallus
Q9DGG6
1334
149273
K608
K
A
L
K
H
V
E
K
P
K
P
C
P
S
C
Frog
Xenopus laevis
P98999
1305
145393
E617
H
T
N
C
T
Q
P
E
T
L
K
S
C
P
S
Zebra Danio
Brachydanio rerio
XP_002661140
597
66839
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624914
729
83737
M67
R
Q
R
T
T
E
E
M
T
P
L
E
M
E
E
Nematode Worm
Caenorhab. elegans
NP_497970
1253
140709
K578
R
S
T
Q
L
L
P
K
E
S
N
S
I
C
I
Sea Urchin
Strong. purpuratus
XP_798394
1073
120672
G411
A
S
L
D
G
A
S
G
S
A
A
N
A
M
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
58.6
92.9
N.A.
92.1
26
N.A.
47.3
80.4
69.9
21.3
N.A.
N.A.
23.2
35.2
34.5
Protein Similarity:
100
98.5
59
95.5
N.A.
95.4
43.5
N.A.
52.4
86.8
78.6
30.6
N.A.
N.A.
36.5
52.4
49.9
P-Site Identity:
100
100
6.6
100
N.A.
100
0
N.A.
6.6
13.3
6.6
0
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
100
100
26.6
100
N.A.
100
13.3
N.A.
20
33.3
6.6
0
N.A.
N.A.
13.3
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
31
0
0
8
0
0
0
8
8
0
8
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
8
0
8
8
8
39
% C
% Asp:
31
0
0
8
0
0
0
0
0
31
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
8
16
8
8
0
8
24
0
8
24
% E
% Phe:
0
0
0
0
0
0
0
0
31
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
16
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
8
8
0
8
% I
% Lys:
16
8
0
8
0
0
31
16
0
8
8
0
31
0
0
% K
% Leu:
0
39
24
0
8
8
0
0
8
16
16
31
8
16
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
16
8
0
% M
% Asn:
0
0
8
8
8
0
0
0
0
0
39
8
0
0
8
% N
% Pro:
8
0
0
0
0
0
16
0
8
8
8
0
8
8
0
% P
% Gln:
0
8
0
39
0
16
8
0
0
0
0
0
0
8
8
% Q
% Arg:
16
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
16
0
0
8
8
16
16
16
8
0
16
0
8
8
% S
% Thr:
0
8
16
16
47
0
8
39
16
8
0
0
0
31
0
% T
% Val:
0
0
0
8
0
39
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _