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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY9
All Species:
14.24
Human Site:
S775
Identified Species:
26.11
UniProt:
O60503
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60503
NP_001107.2
1353
150701
S775
Q
E
E
V
I
K
N
S
P
V
K
T
F
A
S
Chimpanzee
Pan troglodytes
XP_510775
1356
150504
S778
S
T
Q
V
I
K
N
S
P
V
K
T
F
A
S
Rhesus Macaque
Macaca mulatta
XP_001095164
805
89192
S290
E
V
L
S
L
A
V
S
I
R
M
V
F
F
L
Dog
Lupus familis
XP_547151
1352
150601
S775
Q
E
E
V
I
K
N
S
P
V
K
T
F
A
S
Cat
Felis silvestris
Mouse
Mus musculus
P51830
1353
150936
S775
Q
E
E
V
I
K
N
S
P
V
K
T
F
A
S
Rat
Rattus norvegicus
P26769
1090
123297
I575
Q
W
L
K
S
E
D
I
Q
R
I
S
L
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511444
787
88031
V272
L
E
V
L
S
L
I
V
S
I
R
M
A
F
F
Chicken
Gallus gallus
Q9DGG6
1334
149273
A757
Q
E
E
V
M
R
N
A
P
V
K
T
F
A
S
Frog
Xenopus laevis
P98999
1305
145393
A767
Q
E
E
V
I
R
M
A
P
V
K
T
F
A
S
Zebra Danio
Brachydanio rerio
XP_002661140
597
66839
M82
S
L
R
T
Q
R
K
M
P
Q
L
F
E
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624914
729
83737
L214
R
K
Q
S
D
L
Q
L
I
R
C
V
Q
D
N
Nematode Worm
Caenorhab. elegans
NP_497970
1253
140709
R726
K
D
V
E
E
E
Y
R
A
H
F
V
D
S
S
Sea Urchin
Strong. purpuratus
XP_798394
1073
120672
F558
I
S
Q
L
S
L
R
F
N
N
S
E
V
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
58.6
92.9
N.A.
92.1
26
N.A.
47.3
80.4
69.9
21.3
N.A.
N.A.
23.2
35.2
34.5
Protein Similarity:
100
98.5
59
95.5
N.A.
95.4
43.5
N.A.
52.4
86.8
78.6
30.6
N.A.
N.A.
36.5
52.4
49.9
P-Site Identity:
100
80
13.3
100
N.A.
100
6.6
N.A.
6.6
80
80
13.3
N.A.
N.A.
0
6.6
0
P-Site Similarity:
100
86.6
26.6
100
N.A.
100
26.6
N.A.
26.6
100
93.3
20
N.A.
N.A.
26.6
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
16
8
0
0
0
8
47
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
8
0
0
0
0
0
8
8
8
% D
% Glu:
8
47
39
8
8
16
0
0
0
0
0
8
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
8
54
16
16
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
0
39
0
8
8
16
8
8
0
0
0
0
% I
% Lys:
8
8
0
8
0
31
8
0
0
0
47
0
0
0
0
% K
% Leu:
8
8
16
16
8
24
0
8
0
0
8
0
8
8
8
% L
% Met:
0
0
0
0
8
0
8
8
0
0
8
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
39
0
8
8
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
54
0
0
0
0
0
0
% P
% Gln:
47
0
24
0
8
0
8
0
8
8
0
0
8
0
0
% Q
% Arg:
8
0
8
0
0
24
8
8
0
24
8
0
0
8
0
% R
% Ser:
16
8
0
16
24
0
0
39
8
0
8
8
0
8
62
% S
% Thr:
0
8
0
8
0
0
0
0
0
0
0
47
0
0
0
% T
% Val:
0
8
16
47
0
0
8
8
0
47
0
24
8
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _