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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY9
All Species:
20.3
Human Site:
S766
Identified Species:
37.22
UniProt:
O60503
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60503
NP_001107.2
1353
150701
S766
L
E
R
S
Y
R
T
S
Y
Q
E
E
V
I
K
Chimpanzee
Pan troglodytes
XP_510775
1356
150504
S769
M
Q
S
A
Y
V
T
S
C
S
T
Q
V
I
K
Rhesus Macaque
Macaca mulatta
XP_001095164
805
89192
L281
A
V
F
S
A
A
L
L
L
E
V
L
S
L
A
Dog
Lupus familis
XP_547151
1352
150601
S766
L
E
R
S
Y
R
T
S
Y
Q
E
E
V
I
K
Cat
Felis silvestris
Mouse
Mus musculus
P51830
1353
150936
S766
L
E
R
S
Y
R
T
S
Y
Q
E
E
V
I
K
Rat
Rattus norvegicus
P26769
1090
123297
Q566
A
I
D
G
I
N
A
Q
K
Q
W
L
K
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511444
787
88031
I263
V
G
V
F
I
I
A
I
L
L
E
V
L
S
L
Chicken
Gallus gallus
Q9DGG6
1334
149273
S748
L
E
M
A
Y
R
T
S
Y
Q
E
E
V
M
R
Frog
Xenopus laevis
P98999
1305
145393
S758
L
E
T
S
Y
R
A
S
Y
Q
E
E
V
I
R
Zebra Danio
Brachydanio rerio
XP_002661140
597
66839
V73
S
A
I
R
K
P
V
V
K
S
L
R
T
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624914
729
83737
K205
T
F
G
A
C
F
H
K
L
R
K
Q
S
D
L
Nematode Worm
Caenorhab. elegans
NP_497970
1253
140709
N717
N
K
W
T
L
R
F
N
E
K
D
V
E
E
E
Sea Urchin
Strong. purpuratus
XP_798394
1073
120672
P549
E
M
D
Y
F
E
K
P
P
I
S
Q
L
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
58.6
92.9
N.A.
92.1
26
N.A.
47.3
80.4
69.9
21.3
N.A.
N.A.
23.2
35.2
34.5
Protein Similarity:
100
98.5
59
95.5
N.A.
95.4
43.5
N.A.
52.4
86.8
78.6
30.6
N.A.
N.A.
36.5
52.4
49.9
P-Site Identity:
100
40
6.6
100
N.A.
100
6.6
N.A.
6.6
73.3
80
0
N.A.
N.A.
0
6.6
0
P-Site Similarity:
100
66.6
20
100
N.A.
100
13.3
N.A.
20
93.3
86.6
6.6
N.A.
N.A.
26.6
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
24
8
8
24
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
0
0
0
0
0
0
8
0
0
8
0
% D
% Glu:
8
39
0
0
0
8
0
0
8
8
47
39
8
8
16
% E
% Phe:
0
8
8
8
8
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
16
8
0
8
0
8
0
0
0
39
0
% I
% Lys:
0
8
0
0
8
0
8
8
16
8
8
0
8
0
31
% K
% Leu:
39
0
0
0
8
0
8
8
24
8
8
16
16
8
24
% L
% Met:
8
8
8
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
8
8
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
8
0
47
0
24
0
8
0
% Q
% Arg:
0
0
24
8
0
47
0
0
0
8
0
8
0
0
24
% R
% Ser:
8
0
8
39
0
0
0
47
0
16
8
0
16
24
0
% S
% Thr:
8
0
8
8
0
0
39
0
0
0
8
0
8
0
0
% T
% Val:
8
8
8
0
0
8
8
8
0
0
8
16
47
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
8
47
0
0
0
39
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _