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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY9
All Species:
3.64
Human Site:
S665
Identified Species:
6.67
UniProt:
O60503
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60503
NP_001107.2
1353
150701
S665
H
K
N
S
T
K
A
S
G
G
P
N
P
K
T
Chimpanzee
Pan troglodytes
XP_510775
1356
150504
P668
S
T
K
A
S
G
G
P
N
P
K
T
Q
N
G
Rhesus Macaque
Macaca mulatta
XP_001095164
805
89192
F180
R
E
K
T
D
A
H
F
V
D
V
I
K
E
D
Dog
Lupus familis
XP_547151
1352
150601
P665
H
K
N
S
T
K
A
P
G
A
P
N
S
K
T
Cat
Felis silvestris
Mouse
Mus musculus
P51830
1353
150936
S665
P
K
T
S
T
K
A
S
G
G
P
N
S
K
T
Rat
Rattus norvegicus
P26769
1090
123297
P465
K
T
Y
F
V
I
N
P
K
G
E
R
R
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511444
787
88031
H162
I
R
E
K
T
D
A
H
F
V
D
V
I
K
E
Chicken
Gallus gallus
Q9DGG6
1334
149273
P647
H
K
N
S
T
K
A
P
G
G
H
S
P
K
T
Frog
Xenopus laevis
P98999
1305
145393
A657
G
G
A
P
R
P
S
A
I
G
A
S
L
K
D
Zebra Danio
Brachydanio rerio
XP_002661140
597
66839
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624914
729
83737
E104
R
Q
N
T
S
Q
S
E
I
E
M
D
P
N
P
Nematode Worm
Caenorhab. elegans
NP_497970
1253
140709
E616
D
T
N
N
T
Y
S
E
R
G
V
A
G
S
V
Sea Urchin
Strong. purpuratus
XP_798394
1073
120672
N448
L
L
A
S
N
T
T
N
G
A
S
G
S
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
58.6
92.9
N.A.
92.1
26
N.A.
47.3
80.4
69.9
21.3
N.A.
N.A.
23.2
35.2
34.5
Protein Similarity:
100
98.5
59
95.5
N.A.
95.4
43.5
N.A.
52.4
86.8
78.6
30.6
N.A.
N.A.
36.5
52.4
49.9
P-Site Identity:
100
0
0
80
N.A.
80
6.6
N.A.
20
80
13.3
0
N.A.
N.A.
13.3
20
13.3
P-Site Similarity:
100
13.3
20
80
N.A.
80
6.6
N.A.
26.6
86.6
33.3
0
N.A.
N.A.
53.3
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
0
8
39
8
0
16
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
8
0
0
0
8
8
8
0
0
16
% D
% Glu:
0
8
8
0
0
0
0
16
0
8
8
0
0
8
8
% E
% Phe:
0
0
0
8
0
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
0
8
8
0
39
47
0
8
8
8
16
% G
% His:
24
0
0
0
0
0
8
8
0
0
8
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
16
0
0
8
8
0
0
% I
% Lys:
8
31
16
8
0
31
0
0
8
0
8
0
8
47
0
% K
% Leu:
8
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
39
8
8
0
8
8
8
0
0
24
0
16
0
% N
% Pro:
8
0
0
8
0
8
0
31
0
8
24
0
24
0
16
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
0
0
8
0
0
% Q
% Arg:
16
8
0
0
8
0
0
0
8
0
0
8
8
0
0
% R
% Ser:
8
0
0
39
16
0
24
16
0
0
8
16
24
16
0
% S
% Thr:
0
24
8
16
47
8
8
0
0
0
0
8
0
0
31
% T
% Val:
0
0
0
0
8
0
0
0
8
8
16
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _