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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY9
All Species:
14.24
Human Site:
S39
Identified Species:
26.11
UniProt:
O60503
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60503
NP_001107.2
1353
150701
S39
I
N
P
K
Q
L
S
S
N
S
H
P
K
H
C
Chimpanzee
Pan troglodytes
XP_510775
1356
150504
S39
I
N
P
K
Q
L
S
S
N
S
H
P
K
H
C
Rhesus Macaque
Macaca mulatta
XP_001095164
805
89192
Dog
Lupus familis
XP_547151
1352
150601
S39
I
N
P
R
Q
L
S
S
N
S
H
P
K
H
C
Cat
Felis silvestris
Mouse
Mus musculus
P51830
1353
150936
S39
I
N
P
K
Q
L
S
S
N
T
H
P
K
H
C
Rat
Rattus norvegicus
P26769
1090
123297
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511444
787
88031
Chicken
Gallus gallus
Q9DGG6
1334
149273
A39
I
N
P
R
Q
Q
Q
A
L
S
A
K
R
C
K
Frog
Xenopus laevis
P98999
1305
145393
S39
R
Q
H
H
Q
A
P
S
R
R
C
K
Y
S
I
Zebra Danio
Brachydanio rerio
XP_002661140
597
66839
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624914
729
83737
Nematode Worm
Caenorhab. elegans
NP_497970
1253
140709
R39
L
F
E
R
A
S
A
R
W
W
N
P
Q
F
R
Sea Urchin
Strong. purpuratus
XP_798394
1073
120672
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
58.6
92.9
N.A.
92.1
26
N.A.
47.3
80.4
69.9
21.3
N.A.
N.A.
23.2
35.2
34.5
Protein Similarity:
100
98.5
59
95.5
N.A.
95.4
43.5
N.A.
52.4
86.8
78.6
30.6
N.A.
N.A.
36.5
52.4
49.9
P-Site Identity:
100
100
0
93.3
N.A.
93.3
0
N.A.
0
33.3
13.3
0
N.A.
N.A.
0
6.6
0
P-Site Similarity:
100
100
0
100
N.A.
100
0
N.A.
0
53.3
13.3
0
N.A.
N.A.
0
40
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
8
8
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
31
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
8
0
0
0
0
0
0
31
0
0
31
0
% H
% Ile:
39
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
24
0
0
0
0
0
0
0
16
31
0
8
% K
% Leu:
8
0
0
0
0
31
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
39
0
0
0
0
0
0
31
0
8
0
0
0
0
% N
% Pro:
0
0
39
0
0
0
8
0
0
0
0
39
0
0
0
% P
% Gln:
0
8
0
0
47
8
8
0
0
0
0
0
8
0
0
% Q
% Arg:
8
0
0
24
0
0
0
8
8
8
0
0
8
0
8
% R
% Ser:
0
0
0
0
0
8
31
39
0
31
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _