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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOK2
All Species:
16.36
Human Site:
Y357
Identified Species:
40
UniProt:
O60496
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60496
NP_003965.2
412
45379
Y357
G
V
A
A
L
S
L
Y
D
S
P
Q
E
P
R
Chimpanzee
Pan troglodytes
XP_519640
412
45373
Y357
G
V
A
A
L
S
L
Y
D
S
P
Q
E
P
R
Rhesus Macaque
Macaca mulatta
XP_001114039
206
22378
R158
Y
D
S
L
Q
E
P
R
G
E
A
W
R
R
Q
Dog
Lupus familis
XP_543259
411
45419
Y356
G
L
A
A
L
S
L
Y
D
S
P
Q
E
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
O70469
412
45504
Y363
G
V
A
A
L
S
L
Y
D
R
T
Q
R
P
S
Rat
Rattus norvegicus
Q4QQV2
480
52151
Q380
R
G
L
Y
D
L
P
Q
E
P
K
D
A
W
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506018
432
47473
Y369
G
I
A
V
L
T
L
Y
D
R
P
Q
E
P
Q
Chicken
Gallus gallus
A3R064
426
47148
W354
A
E
E
E
E
G
R
W
E
L
G
C
R
Q
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998253
575
63920
I448
A
G
S
S
Q
P
V
I
T
L
Y
D
E
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792985
602
64705
A460
G
A
V
G
S
T
A
A
D
A
Q
Q
V
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
46.5
84.2
N.A.
74.5
34.5
N.A.
64.8
33.7
N.A.
33
N.A.
N.A.
N.A.
N.A.
23.9
Protein Similarity:
100
99.5
47.3
87.8
N.A.
79.3
45.2
N.A.
74
48.1
N.A.
44.7
N.A.
N.A.
N.A.
N.A.
35.8
P-Site Identity:
100
100
0
86.6
N.A.
73.3
0
N.A.
66.6
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
13.3
100
N.A.
73.3
6.6
N.A.
86.6
13.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
50
40
0
0
10
10
0
10
10
0
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
10
0
0
10
0
0
0
60
0
0
20
0
0
0
% D
% Glu:
0
10
10
10
10
10
0
0
20
10
0
0
50
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
60
20
0
10
0
10
0
0
10
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
10
10
10
50
10
50
0
0
20
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
20
0
0
10
40
0
0
50
0
% P
% Gln:
0
0
0
0
20
0
0
10
0
0
10
60
0
10
30
% Q
% Arg:
10
0
0
0
0
0
10
10
0
20
0
0
30
10
30
% R
% Ser:
0
0
20
10
10
40
0
0
0
30
0
0
0
0
20
% S
% Thr:
0
0
0
0
0
20
0
0
10
0
10
0
0
0
0
% T
% Val:
0
30
10
10
0
0
10
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
10
0
10
10
% W
% Tyr:
10
0
0
10
0
0
0
50
0
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _