Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOK2 All Species: 16.36
Human Site: Y170 Identified Species: 40
UniProt: O60496 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60496 NP_003965.2 412 45379 Y170 R C H L R G S Y T L R A G E S
Chimpanzee Pan troglodytes XP_519640 412 45373 Y170 R C H L R G S Y T L R A G E S
Rhesus Macaque Macaca mulatta XP_001114039 206 22378
Dog Lupus familis XP_543259 411 45419 Y169 R C R L R F S Y T L R A G E N
Cat Felis silvestris
Mouse Mus musculus O70469 412 45504 Y172 R C R L R G S Y T L R T G V S
Rat Rattus norvegicus Q4QQV2 480 52151 R177 L Q G S Y V L R V E A E K L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506018 432 47473 Y173 R C R L R G S Y V L R T G E S
Chicken Gallus gallus A3R064 426 47148 H167 A R C E L H G H Y V L A A L P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998253 575 63920 N169 E R C G L S G N Y W L R A N M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792985 602 64705 S174 D S L N L H G S Y A L Q L D S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 46.5 84.2 N.A. 74.5 34.5 N.A. 64.8 33.7 N.A. 33 N.A. N.A. N.A. N.A. 23.9
Protein Similarity: 100 99.5 47.3 87.8 N.A. 79.3 45.2 N.A. 74 48.1 N.A. 44.7 N.A. N.A. N.A. N.A. 35.8
P-Site Identity: 100 100 0 80 N.A. 80 0 N.A. 80 6.6 N.A. 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 0 86.6 N.A. 80 6.6 N.A. 80 20 N.A. 0 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 10 10 40 20 0 0 % A
% Cys: 0 50 20 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 10 0 0 10 0 0 0 0 0 10 0 10 0 40 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 10 0 40 30 0 0 0 0 0 50 0 0 % G
% His: 0 0 20 0 0 20 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % K
% Leu: 10 0 10 50 30 0 10 0 0 50 30 0 10 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 10 0 0 0 10 0 0 0 0 0 10 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 50 20 30 0 50 0 0 10 0 0 50 10 0 0 0 % R
% Ser: 0 10 0 10 0 10 50 10 0 0 0 0 0 0 50 % S
% Thr: 0 0 0 0 0 0 0 0 40 0 0 20 0 0 10 % T
% Val: 0 0 0 0 0 10 0 0 20 10 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 50 30 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _