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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOK2
All Species:
5.76
Human Site:
T336
Identified Species:
14.07
UniProt:
O60496
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60496
NP_003965.2
412
45379
T336
L
Y
D
S
I
E
E
T
L
P
P
R
P
D
H
Chimpanzee
Pan troglodytes
XP_519640
412
45373
T336
L
Y
D
S
I
E
E
T
L
P
S
R
P
D
H
Rhesus Macaque
Macaca mulatta
XP_001114039
206
22378
H137
P
P
P
P
R
H
D
H
I
Y
D
E
P
E
G
Dog
Lupus familis
XP_543259
411
45419
H335
L
Y
D
S
I
E
E
H
P
P
P
R
P
D
H
Cat
Felis silvestris
Mouse
Mus musculus
O70469
412
45504
P342
Y
D
S
I
Q
E
D
P
G
A
P
L
P
D
H
Rat
Rattus norvegicus
Q4QQV2
480
52151
P359
L
I
D
S
K
E
D
P
I
Y
D
E
P
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506018
432
47473
E348
P
L
Y
D
S
I
D
E
R
P
S
L
P
D
P
Chicken
Gallus gallus
A3R064
426
47148
N333
L
P
E
H
L
Y
E
N
I
F
T
A
Q
P
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998253
575
63920
G427
R
S
R
H
P
A
D
G
G
P
T
E
H
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792985
602
64705
S439
A
A
V
F
L
D
E
S
E
D
P
G
L
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
46.5
84.2
N.A.
74.5
34.5
N.A.
64.8
33.7
N.A.
33
N.A.
N.A.
N.A.
N.A.
23.9
Protein Similarity:
100
99.5
47.3
87.8
N.A.
79.3
45.2
N.A.
74
48.1
N.A.
44.7
N.A.
N.A.
N.A.
N.A.
35.8
P-Site Identity:
100
93.3
6.6
86.6
N.A.
33.3
33.3
N.A.
20
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
26.6
86.6
N.A.
40
53.3
N.A.
26.6
33.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
10
0
0
0
10
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
40
10
0
10
50
0
0
10
20
0
0
50
0
% D
% Glu:
0
0
10
0
0
50
50
10
10
0
0
30
0
20
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
20
0
0
10
0
0
20
% G
% His:
0
0
0
20
0
10
0
20
0
0
0
0
10
0
40
% H
% Ile:
0
10
0
10
30
10
0
0
30
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
50
10
0
0
20
0
0
0
20
0
0
20
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
20
20
10
10
10
0
0
20
10
50
40
0
70
10
10
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
10
0
10
0
10
0
0
0
10
0
0
30
0
0
10
% R
% Ser:
0
10
10
40
10
0
0
10
0
0
20
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
20
0
0
20
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
30
10
0
0
10
0
0
0
20
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _