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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1B All Species: 20.91
Human Site: S1246 Identified Species: 38.33
UniProt: O60333 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60333 NP_055889.2 1816 204476 S1246 S K T S L G Q S M S K Y D L L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536743 1407 158778 A874 P T G E Y I P A V V D H T A G
Cat Felis silvestris
Mouse Mus musculus Q60575 1816 204062 S1246 N K T T L G Q S M S K Y D L L
Rat Rattus norvegicus O88658 1816 204151 S1246 N K T S L G Q S M S K Y D L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509769 1770 199343 S1200 S K T S L G Q S M S K Y D L L
Chicken Gallus gallus XP_417608 1757 197902 S1200 S K P S L G Q S V S K Y D L L
Frog Xenopus laevis Q91784 1226 138905 E693 Q Y E L L K L E R D F Q K Q A
Zebra Danio Brachydanio rerio NP_919363 1770 199169 C1198 T K S N L G Q C V S K Y D L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 E1137 E Y V P S V V E H S D D L P C
Honey Bee Apis mellifera XP_397276 1682 191012 G1146 G L F L L H Q G I Q R R I R I
Nematode Worm Caenorhab. elegans P23678 1584 179603 S1051 N N N A S V K S K H D L L V W
Sea Urchin Strong. purpuratus P46872 699 78679 L166 G K D Q Q H R L E V K E R P D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 S395 L E L A I T P S K S A S T T A
Conservation
Percent
Protein Identity: 100 N.A. N.A. 75.5 N.A. 97 96.8 N.A. 93.2 92.7 23.8 85.6 N.A. 54.2 56.8 49.3 20.5
Protein Similarity: 100 N.A. N.A. 76.5 N.A. 98.9 98.7 N.A. 95.8 95.1 40.7 91.5 N.A. 69.7 70.5 64.2 28.5
P-Site Identity: 100 N.A. N.A. 0 N.A. 86.6 93.3 N.A. 100 86.6 6.6 66.6 N.A. 6.6 13.3 6.6 13.3
P-Site Similarity: 100 N.A. N.A. 20 N.A. 100 100 N.A. 100 93.3 6.6 93.3 N.A. 6.6 33.3 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 23.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 0 0 0 8 0 0 8 0 0 8 16 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % C
% Asp: 0 0 8 0 0 0 0 0 0 8 24 8 47 0 8 % D
% Glu: 8 8 8 8 0 0 0 16 8 0 0 8 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 16 0 8 0 0 47 0 8 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 16 0 0 8 8 0 8 0 0 0 % H
% Ile: 0 0 0 0 8 8 0 0 8 0 0 0 8 0 8 % I
% Lys: 0 54 0 0 0 8 8 0 16 0 54 0 8 0 0 % K
% Leu: 8 8 8 16 62 0 8 8 0 0 0 8 16 47 47 % L
% Met: 0 0 0 0 0 0 0 0 31 0 0 0 0 0 0 % M
% Asn: 24 8 8 8 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 8 8 0 0 16 0 0 0 0 0 0 16 0 % P
% Gln: 8 0 0 8 8 0 54 0 0 8 0 8 0 8 0 % Q
% Arg: 0 0 0 0 0 0 8 0 8 0 8 8 8 8 0 % R
% Ser: 24 0 8 31 16 0 0 54 0 62 0 8 0 0 0 % S
% Thr: 8 8 31 8 0 8 0 0 0 0 0 0 16 8 0 % T
% Val: 0 0 8 0 0 16 8 0 24 16 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 16 0 0 8 0 0 0 0 0 0 47 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _