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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCMT2
All Species:
32.12
Human Site:
Y218
Identified Species:
78.52
UniProt:
O60294
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60294
NP_055608.2
686
75602
Y218
P
N
A
L
F
V
V
Y
E
Q
M
R
P
Q
D
Chimpanzee
Pan troglodytes
XP_001157403
686
75594
Y218
P
N
A
L
F
V
V
Y
E
Q
M
R
P
Q
D
Rhesus Macaque
Macaca mulatta
XP_001106399
705
77724
Y218
P
N
A
L
F
V
V
Y
E
Q
M
R
P
Q
D
Dog
Lupus familis
XP_544648
687
75289
Y218
P
D
A
L
F
V
I
Y
E
Q
M
R
P
H
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR1
686
75245
Y218
P
D
A
L
F
V
I
Y
E
Q
M
Q
P
G
D
Rat
Rattus norvegicus
Q5XIA3
686
75514
Y218
P
N
A
L
F
V
I
Y
E
Q
M
K
P
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417263
744
82265
Y276
S
H
A
C
F
L
L
Y
E
Q
M
H
P
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001122029
673
74152
Y219
P
Q
S
M
F
V
M
Y
E
Q
I
H
P
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792604
724
79488
Y246
P
N
G
Q
F
V
S
Y
E
Q
V
L
P
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08282
695
78956
L253
E
N
S
H
F
I
I
L
E
Q
L
I
P
K
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
93.1
82.9
N.A.
77.9
77.2
N.A.
N.A.
47.8
N.A.
46
N.A.
N.A.
N.A.
N.A.
40.1
Protein Similarity:
100
99.8
94.8
89.6
N.A.
86.1
85.2
N.A.
N.A.
62.2
N.A.
62.9
N.A.
N.A.
N.A.
N.A.
57.6
P-Site Identity:
100
100
100
80
N.A.
73.3
80
N.A.
N.A.
53.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
N.A.
80
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
0
0
0
0
0
0
0
0
20
90
% D
% Glu:
10
0
0
0
0
0
0
0
100
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
20
10
% G
% His:
0
10
0
10
0
0
0
0
0
0
0
20
0
10
0
% H
% Ile:
0
0
0
0
0
10
40
0
0
0
10
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
0
0
0
60
0
10
10
10
0
0
10
10
0
0
0
% L
% Met:
0
0
0
10
0
0
10
0
0
0
70
0
0
0
0
% M
% Asn:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
80
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% P
% Gln:
0
10
0
10
0
0
0
0
0
100
0
10
0
30
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
40
0
0
0
% R
% Ser:
10
0
20
0
0
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
80
30
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
90
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _