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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LCMT2 All Species: 17.88
Human Site: S398 Identified Species: 43.7
UniProt: O60294 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60294 NP_055608.2 686 75602 S398 L L S R D C D S E W K G S Q I
Chimpanzee Pan troglodytes XP_001157403 686 75594 S398 L L S R D C D S E W K G S Q I
Rhesus Macaque Macaca mulatta XP_001106399 705 77724 S398 L L S R D G D S E W K G S Q I
Dog Lupus familis XP_544648 687 75289 F398 L L S R F C D F E W K G N Q I
Cat Felis silvestris
Mouse Mus musculus Q8BYR1 686 75245 S398 V L S R S C D S E W E G C Q I
Rat Rattus norvegicus Q5XIA3 686 75514 S398 L L S R S C D S E W K G C Q I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417263 744 82265 S456 V L I K Y A G S W K T K C V K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001122029 673 74152 A385 R N G R D T A A R V L I K E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792604 724 79488 L437 E K V Q M V N L D L G T I E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08282 695 78956 N407 V F Y M G G S N P Y R V N E I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 93.1 82.9 N.A. 77.9 77.2 N.A. N.A. 47.8 N.A. 46 N.A. N.A. N.A. N.A. 40.1
Protein Similarity: 100 99.8 94.8 89.6 N.A. 86.1 85.2 N.A. N.A. 62.2 N.A. 62.9 N.A. N.A. N.A. N.A. 57.6
P-Site Identity: 100 100 93.3 80 N.A. 73.3 86.6 N.A. N.A. 13.3 N.A. 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. N.A. 26.6 N.A. 26.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 10 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 50 0 0 0 0 0 0 30 0 0 % C
% Asp: 0 0 0 0 40 0 60 0 10 0 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 60 0 10 0 0 30 10 % E
% Phe: 0 10 0 0 10 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 10 20 10 0 0 0 10 60 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 10 10 0 70 % I
% Lys: 0 10 0 10 0 0 0 0 0 10 50 10 10 0 20 % K
% Leu: 50 70 0 0 0 0 0 10 0 10 10 0 0 0 0 % L
% Met: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 10 10 0 0 0 0 20 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 0 60 0 % Q
% Arg: 10 0 0 70 0 0 0 0 10 0 10 0 0 0 0 % R
% Ser: 0 0 60 0 20 0 10 60 0 0 0 0 30 0 0 % S
% Thr: 0 0 0 0 0 10 0 0 0 0 10 10 0 0 0 % T
% Val: 30 0 10 0 0 10 0 0 0 10 0 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 60 0 0 0 0 0 % W
% Tyr: 0 0 10 0 10 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _