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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLK8
All Species:
25.45
Human Site:
Y242
Identified Species:
80
UniProt:
O60259
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60259
NP_009127.1
260
28048
Y242
R
S
D
K
P
G
V
Y
T
N
I
C
R
Y
L
Chimpanzee
Pan troglodytes
XP_001174106
305
32964
Y287
R
S
D
K
P
G
V
Y
T
N
I
C
R
Y
L
Rhesus Macaque
Macaca mulatta
XP_001116177
242
26567
Y225
N
T
T
K
P
G
V
Y
T
K
V
C
H
Y
L
Dog
Lupus familis
XP_541468
259
28217
Y241
R
P
E
R
P
G
V
Y
T
N
I
C
R
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61955
260
28505
Y242
K
P
E
K
P
G
V
Y
T
K
I
C
R
Y
T
Rat
Rattus norvegicus
O88780
260
28491
Y242
K
P
E
K
P
G
V
Y
T
K
I
C
R
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90629
248
26604
Y231
L
K
G
Y
P
G
V
Y
T
K
V
C
N
Y
V
Frog
Xenopus laevis
P70059
244
26061
Y227
Q
R
N
Y
P
G
V
Y
T
K
V
C
N
F
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.2
45.7
77.6
N.A.
71.9
71.5
N.A.
N.A.
41.1
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
85.2
62.3
86.5
N.A.
84.6
85
N.A.
N.A.
58.8
57.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
60
80
N.A.
66.6
66.6
N.A.
N.A.
46.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
93.3
N.A.
80
80
N.A.
N.A.
60
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% C
% Asp:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
38
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% F
% Gly:
0
0
13
0
0
100
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
63
0
0
0
0
% I
% Lys:
25
13
0
63
0
0
0
0
0
63
0
0
0
0
0
% K
% Leu:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
13
0
0
0
0
0
0
38
0
0
25
0
0
% N
% Pro:
0
38
0
0
100
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
38
13
0
13
0
0
0
0
0
0
0
0
63
0
0
% R
% Ser:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
13
13
0
0
0
0
0
100
0
0
0
0
0
25
% T
% Val:
0
0
0
0
0
0
100
0
0
0
38
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
25
0
0
0
100
0
0
0
0
0
88
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _