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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED14
All Species:
21.21
Human Site:
Y569
Identified Species:
46.67
UniProt:
O60244
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60244
NP_004220.2
1454
160607
Y569
T
Q
L
S
Y
K
Y
Y
F
M
S
V
N
A
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085867
1454
160592
Y569
T
Q
L
S
Y
K
Y
Y
F
M
S
V
N
A
A
Dog
Lupus familis
XP_538001
1454
160675
Y569
T
Q
L
S
Y
K
Y
Y
F
M
S
V
N
A
A
Cat
Felis silvestris
Mouse
Mus musculus
A2ABV5
1459
160947
Y575
T
Q
L
S
Y
N
Y
Y
F
M
S
V
S
T
A
Rat
Rattus norvegicus
XP_228713
1459
160778
Y575
T
Q
L
S
Y
K
Y
Y
F
M
S
V
S
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512965
1393
154376
H510
T
E
L
E
Y
K
Y
H
F
L
S
V
S
F
A
Chicken
Gallus gallus
XP_416776
1446
160107
Y558
T
E
L
E
Y
K
Y
Y
F
L
S
V
S
Y
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997930
604
65219
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0P8
1553
172323
H552
N
E
M
E
Y
T
F
H
L
G
F
V
A
Y
Q
Honey Bee
Apis mellifera
XP_625172
1433
159084
N506
D
N
E
T
P
E
T
N
S
L
K
R
R
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782925
684
74105
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
98.6
N.A.
96.5
96.7
N.A.
89.4
90.3
N.A.
35.1
N.A.
36.7
38.7
N.A.
20
Protein Similarity:
100
N.A.
99.9
99.3
N.A.
98.2
98.1
N.A.
92.7
94.7
N.A.
37.8
N.A.
54.7
57.5
N.A.
30.1
P-Site Identity:
100
N.A.
100
100
N.A.
80
86.6
N.A.
60
66.6
N.A.
0
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
93.3
N.A.
86.6
86.6
N.A.
0
N.A.
40
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
28
64
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
28
10
28
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
64
0
10
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
55
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
64
0
0
0
0
0
10
28
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
46
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
10
0
10
0
0
0
0
28
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
46
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% R
% Ser:
0
0
0
46
0
0
0
0
10
0
64
0
37
10
0
% S
% Thr:
64
0
0
10
0
10
10
0
0
0
0
0
0
19
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
73
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
73
0
64
55
0
0
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _