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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED14 All Species: 26.97
Human Site: Y1019 Identified Species: 59.33
UniProt: O60244 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60244 NP_004220.2 1454 160607 Y1019 Q P G T S G A Y P L T S P P T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001085867 1454 160592 Y1019 Q P G T S G A Y P L T S P P T
Dog Lupus familis XP_538001 1454 160675 Y1019 Q P G S S G A Y P L T S P P T
Cat Felis silvestris
Mouse Mus musculus A2ABV5 1459 160947 Y1024 Q P G T S G A Y P L T S P P T
Rat Rattus norvegicus XP_228713 1459 160778 Y1024 Q P G T S G A Y P L T S P P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512965 1393 154376 Y958 Q P G S S G A Y P L T S P P T
Chicken Gallus gallus XP_416776 1446 160107 Y1012 Q A G A S G A Y P L T S P P T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_997930 604 65219 L184 L N Q L N Q I L R H R L V T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0P8 1553 172323 P1048 L G T G M R G P Q S P R D S G
Honey Bee Apis mellifera XP_625172 1433 159084 T942 H T P A S P H T A N I S Q T N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782925 684 74105 P264 G S S N P A T P A S P H T S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 98.6 N.A. 96.5 96.7 N.A. 89.4 90.3 N.A. 35.1 N.A. 36.7 38.7 N.A. 20
Protein Similarity: 100 N.A. 99.9 99.3 N.A. 98.2 98.1 N.A. 92.7 94.7 N.A. 37.8 N.A. 54.7 57.5 N.A. 30.1
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 93.3 N.A. 93.3 86.6 N.A. 6.6 N.A. 0 13.3 N.A. 0
P-Site Similarity: 100 N.A. 100 100 N.A. 100 93.3 N.A. 100 86.6 N.A. 13.3 N.A. 0 13.3 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 19 0 10 64 0 19 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 64 10 0 64 10 0 0 0 0 0 0 0 10 % G
% His: 10 0 0 0 0 0 10 0 0 10 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 19 0 0 10 0 0 0 10 0 64 0 10 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 10 10 0 0 0 0 10 0 0 0 0 10 % N
% Pro: 0 55 10 0 10 10 0 19 64 0 19 0 64 64 0 % P
% Gln: 64 0 10 0 0 10 0 0 10 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 10 0 0 10 0 10 10 0 0 0 % R
% Ser: 0 10 10 19 73 0 0 0 0 19 0 73 0 19 0 % S
% Thr: 0 10 10 37 0 0 10 10 0 0 64 0 10 19 64 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 64 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _