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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED14
All Species:
22.73
Human Site:
T349
Identified Species:
50
UniProt:
O60244
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60244
NP_004220.2
1454
160607
T349
Q
Q
V
L
G
R
K
T
G
T
A
S
V
H
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085867
1454
160592
T349
Q
Q
V
L
G
R
K
T
G
T
A
S
V
H
K
Dog
Lupus familis
XP_538001
1454
160675
T349
Q
Q
V
L
G
R
K
T
G
T
A
S
V
H
K
Cat
Felis silvestris
Mouse
Mus musculus
A2ABV5
1459
160947
T355
Q
Q
V
L
G
R
K
T
G
T
A
S
V
H
K
Rat
Rattus norvegicus
XP_228713
1459
160778
T355
Q
Q
V
L
G
R
K
T
G
T
A
S
V
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512965
1393
154376
K309
I
D
E
N
D
V
S
K
P
L
Q
I
F
H
D
Chicken
Gallus gallus
XP_416776
1446
160107
T338
Q
Q
V
L
G
R
K
T
G
T
A
S
V
H
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997930
604
65219
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0P8
1553
172323
Y336
D
L
K
S
E
L
G
Y
R
L
T
V
Q
S
D
Honey Bee
Apis mellifera
XP_625172
1433
159084
D307
E
L
Q
T
M
L
K
D
V
E
C
T
L
A
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782925
684
74105
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
98.6
N.A.
96.5
96.7
N.A.
89.4
90.3
N.A.
35.1
N.A.
36.7
38.7
N.A.
20
Protein Similarity:
100
N.A.
99.9
99.3
N.A.
98.2
98.1
N.A.
92.7
94.7
N.A.
37.8
N.A.
54.7
57.5
N.A.
30.1
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
100
N.A.
0
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
100
N.A.
0
N.A.
0
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
55
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
10
0
0
10
0
0
10
0
0
0
0
0
0
19
% D
% Glu:
10
0
10
0
10
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
55
0
10
0
55
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
64
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
10
0
0
0
64
10
0
0
0
0
0
0
55
% K
% Leu:
0
19
0
55
0
19
0
0
0
19
0
0
10
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
55
55
10
0
0
0
0
0
0
0
10
0
10
0
0
% Q
% Arg:
0
0
0
0
0
55
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
10
0
0
0
0
55
0
10
0
% S
% Thr:
0
0
0
10
0
0
0
55
0
55
10
10
0
0
0
% T
% Val:
0
0
55
0
0
10
0
0
10
0
0
10
55
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _