KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED14
All Species:
23.64
Human Site:
S1393
Identified Species:
52
UniProt:
O60244
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60244
NP_004220.2
1454
160607
S1393
P
I
I
Y
D
M
A
S
G
T
T
Q
Q
A
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085867
1454
160592
S1393
P
I
I
Y
D
M
A
S
G
T
T
Q
Q
A
D
Dog
Lupus familis
XP_538001
1454
160675
S1393
P
I
I
Y
D
M
A
S
G
T
T
Q
Q
A
D
Cat
Felis silvestris
Mouse
Mus musculus
A2ABV5
1459
160947
S1398
P
I
I
Y
D
M
A
S
G
T
T
Q
Q
A
D
Rat
Rattus norvegicus
XP_228713
1459
160778
S1398
P
I
I
Y
D
M
A
S
G
T
T
Q
Q
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512965
1393
154376
S1332
P
I
I
Y
D
M
A
S
G
T
T
Q
Q
A
D
Chicken
Gallus gallus
XP_416776
1446
160107
G1386
I
I
Y
D
M
A
S
G
T
T
Q
Q
A
D
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997930
604
65219
Q547
D
M
A
T
G
L
T
Q
Q
A
D
I
P
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0P8
1553
172323
L1431
K
D
S
P
S
L
V
L
P
I
V
Y
D
I
Q
Honey Bee
Apis mellifera
XP_625172
1433
159084
S1321
L
P
L
V
Y
D
V
S
T
N
L
T
Q
L
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782925
684
74105
M627
I
V
P
V
L
Y
D
M
Q
A
N
T
T
Q
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
98.6
N.A.
96.5
96.7
N.A.
89.4
90.3
N.A.
35.1
N.A.
36.7
38.7
N.A.
20
Protein Similarity:
100
N.A.
99.9
99.3
N.A.
98.2
98.1
N.A.
92.7
94.7
N.A.
37.8
N.A.
54.7
57.5
N.A.
30.1
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
20
N.A.
0
N.A.
0
13.3
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
26.6
N.A.
13.3
N.A.
6.6
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
55
0
0
19
0
0
10
55
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
10
55
10
10
0
0
0
10
0
10
10
55
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
10
55
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
19
64
55
0
0
0
0
0
0
10
0
10
0
10
10
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
10
0
10
19
0
10
0
0
10
0
0
10
0
% L
% Met:
0
10
0
0
10
55
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% N
% Pro:
55
10
10
10
0
0
0
0
10
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
19
0
10
64
64
10
19
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
10
0
10
0
10
64
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
10
0
19
64
55
19
10
0
0
% T
% Val:
0
10
0
19
0
0
19
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
55
10
10
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _