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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED14 All Species: 26.67
Human Site: S1064 Identified Species: 58.67
UniProt: O60244 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60244 NP_004220.2 1454 160607 S1064 L R A P S P A S F V P T P P P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001085867 1454 160592 S1064 L R A P S P A S F V P T P P P
Dog Lupus familis XP_538001 1454 160675 S1064 L R A P S P A S F V P T P P P
Cat Felis silvestris
Mouse Mus musculus A2ABV5 1459 160947 S1069 L R A P S P A S F V P T P P P
Rat Rattus norvegicus XP_228713 1459 160778 S1069 L R A P S P A S F V P T P P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512965 1393 154376 S1003 L R A P S P A S F V P T P P P
Chicken Gallus gallus XP_416776 1446 160107 S1057 L R A P S P A S F G P T P S P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_997930 604 65219 I229 M G D D P G N I H A A N S P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0P8 1553 172323 N1093 S G P Q G H G N F N L T S P P
Honey Bee Apis mellifera XP_625172 1433 159084 L987 H P S P G S G L V A N S P L N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782925 684 74105 G309 M K G T P S P G L V E G G S P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 98.6 N.A. 96.5 96.7 N.A. 89.4 90.3 N.A. 35.1 N.A. 36.7 38.7 N.A. 20
Protein Similarity: 100 N.A. 99.9 99.3 N.A. 98.2 98.1 N.A. 92.7 94.7 N.A. 37.8 N.A. 54.7 57.5 N.A. 30.1
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 86.6 N.A. 6.6 N.A. 26.6 13.3 N.A. 13.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 86.6 N.A. 13.3 N.A. 33.3 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 64 0 0 0 64 0 0 19 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 73 0 0 0 0 0 0 % F
% Gly: 0 19 10 0 19 10 19 10 0 10 0 10 10 0 0 % G
% His: 10 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 64 0 0 0 0 0 0 10 10 0 10 0 0 10 0 % L
% Met: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 10 0 10 10 10 0 0 10 % N
% Pro: 0 10 10 73 19 64 10 0 0 0 64 0 73 73 82 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 64 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 10 0 64 19 0 64 0 0 0 10 19 19 10 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 0 73 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 64 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _