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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TIMM8A All Species: 31.21
Human Site: S87 Identified Species: 42.92
UniProt: O60220 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60220 NP_004076.1 97 10998 S87 R L E Q T Q K S K P V F S E S
Chimpanzee Pan troglodytes XP_001146364 83 9325 F74 T L A I T S R F A Q I V Q K G
Rhesus Macaque Macaca mulatta XP_001095067 139 15567 S129 R L E Q T Q K S K P V F S E S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9WVA2 97 11024 S87 R L E Q T Q K S K P V F S E S
Rat Rattus norvegicus Q9WVA1 97 11024 S87 R L E Q T Q K S K P V F S E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511200 96 10843 S86 R L E Q T Q K S K P A F S E S
Chicken Gallus gallus XP_420185 94 10668 S84 R L E Q T Q K S K S A F S E S
Frog Xenopus laevis Q66L32 94 10390 F85 T L S I T N R F A Q I V Q K G
Zebra Danio Brachydanio rerio Q6DEM5 90 10544 S80 R L E Q T Q R S R G A F S E T
Tiger Blowfish Takifugu rubipres Q90YI5 90 10442 S80 R L E Q T Q R S K G S F S E T
Fruit Fly Dros. melanogaster Q9Y1A3 88 10044 M79 I T Q R F A Q M L Q K R G G G
Honey Bee Apis mellifera XP_001122230 86 9800 R77 V S L L I T N R F A Q L L Q K
Nematode Worm Caenorhab. elegans Q9N408 83 9559 H74 A S N F M V E H L S K M N G G
Sea Urchin Strong. purpuratus XP_001183127 89 10035 S80 N R L E S V K S S P G S K L G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9XGY4 77 8732 M68 Q R Y M D M S M I I M K R F N
Baker's Yeast Sacchar. cerevisiae P57744 87 9745 R78 R F L D T N I R I V N G L Q N
Red Bread Mold Neurospora crassa Q9Y8C0 92 10401 V83 N L T I M A H V Q K I T R G G
Conservation
Percent
Protein Identity: 100 38.1 69 N.A. N.A. 94.8 94.8 N.A. 88.6 85.5 41.2 75.2 73.2 39.1 40.2 34 45.3
Protein Similarity: 100 52.5 69 N.A. N.A. 97.9 96.9 N.A. 92.7 87.6 58.7 84.5 83.5 50.5 54.6 51.5 67
P-Site Identity: 100 13.3 100 N.A. N.A. 100 100 N.A. 93.3 86.6 13.3 66.6 73.3 0 0 0 20
P-Site Similarity: 100 33.3 100 N.A. N.A. 100 100 N.A. 93.3 86.6 33.3 86.6 86.6 20 6.6 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 27.8 31.9 34
Protein Similarity: N.A. N.A. N.A. 49.4 49.4 47.4
P-Site Identity: N.A. N.A. N.A. 0 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. 20 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 6 0 0 12 0 0 12 6 18 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 6 6 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 48 6 0 0 6 0 0 0 0 0 0 48 0 % E
% Phe: 0 6 0 6 6 0 0 12 6 0 0 48 0 6 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 12 6 6 6 18 36 % G
% His: 0 0 0 0 0 0 6 6 0 0 0 0 0 0 0 % H
% Ile: 6 0 0 18 6 0 6 0 12 6 18 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 42 0 42 6 12 6 6 12 6 % K
% Leu: 0 65 18 6 0 0 0 0 12 0 0 6 12 6 0 % L
% Met: 0 0 0 6 12 6 0 12 0 0 6 6 0 0 0 % M
% Asn: 12 0 6 0 0 12 6 0 0 0 6 0 6 0 12 % N
% Pro: 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 % P
% Gln: 6 0 6 48 0 48 6 0 6 18 6 0 12 12 0 % Q
% Arg: 53 12 0 6 0 0 24 12 6 0 0 6 12 0 0 % R
% Ser: 0 12 6 0 6 6 6 53 6 12 6 6 48 0 36 % S
% Thr: 12 6 6 0 65 6 0 0 0 0 0 6 0 0 12 % T
% Val: 6 0 0 0 0 12 0 6 0 6 24 12 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _