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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TIMM8A All Species: 25.45
Human Site: S57 Identified Species: 35
UniProt: O60220 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60220 NP_004076.1 97 10998 S57 K P G P K L D S R A E A C F V
Chimpanzee Pan troglodytes XP_001146364 83 9325 G45 D K C V E K P G N R L D S R T
Rhesus Macaque Macaca mulatta XP_001095067 139 15567 S99 K P G P K L D S R A E A C F V
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9WVA2 97 11024 S57 K P G P K L D S R A E A C F V
Rat Rattus norvegicus Q9WVA1 97 11024 S57 K P G P K L D S R A E A C F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511200 96 10843 S56 K P G P K L D S R A E T C F V
Chicken Gallus gallus XP_420185 94 10668 S54 K P G P K L D S R A E T C F V
Frog Xenopus laevis Q66L32 94 10390 R54 C W D K C I D R P G N K L D S
Zebra Danio Brachydanio rerio Q6DEM5 90 10544 R51 P G P K L D S R T E V C F V N
Tiger Blowfish Takifugu rubipres Q90YI5 90 10442 R51 P G P K L D S R A E M C F V N
Fruit Fly Dros. melanogaster Q9Y1A3 88 10044 L50 I G K P S T K L D H A T E T C
Honey Bee Apis mellifera XP_001122230 86 9800 P48 W D K C I D K P G V K L D S R
Nematode Worm Caenorhab. elegans Q9N408 83 9559 P45 V C F A D Y R P P S K M D G K
Sea Urchin Strong. purpuratus XP_001183127 89 10035 S51 R L G A R L E S K T E S C L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9XGY4 77 8732 C39 T S V C W D K C I T S A P G S
Baker's Yeast Sacchar. cerevisiae P57744 87 9745 V49 N I C F K K C V E S V N D S N
Red Bread Mold Neurospora crassa Q9Y8C0 92 10401 K53 K C V T S P I K T N Q L D K T
Conservation
Percent
Protein Identity: 100 38.1 69 N.A. N.A. 94.8 94.8 N.A. 88.6 85.5 41.2 75.2 73.2 39.1 40.2 34 45.3
Protein Similarity: 100 52.5 69 N.A. N.A. 97.9 96.9 N.A. 92.7 87.6 58.7 84.5 83.5 50.5 54.6 51.5 67
P-Site Identity: 100 0 100 N.A. N.A. 100 100 N.A. 93.3 93.3 6.6 0 0 6.6 0 0 40
P-Site Similarity: 100 6.6 100 N.A. N.A. 100 100 N.A. 93.3 93.3 13.3 0 0 6.6 6.6 13.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. 27.8 31.9 34
Protein Similarity: N.A. N.A. N.A. 49.4 49.4 47.4
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 0 0 0 6 36 6 30 0 0 0 % A
% Cys: 6 12 12 12 6 0 6 6 0 0 0 12 42 0 6 % C
% Asp: 6 6 6 0 6 24 42 0 6 0 0 6 24 6 0 % D
% Glu: 0 0 0 0 6 0 6 0 6 12 42 0 6 0 0 % E
% Phe: 0 0 6 6 0 0 0 0 0 0 0 0 12 36 0 % F
% Gly: 0 18 42 0 0 0 0 6 6 6 0 0 0 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % H
% Ile: 6 6 0 0 6 6 6 0 6 0 0 0 0 0 0 % I
% Lys: 42 6 12 18 42 12 18 6 6 0 12 6 0 6 6 % K
% Leu: 0 6 0 0 12 42 0 6 0 0 6 12 6 6 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 6 6 0 0 0 % M
% Asn: 6 0 0 0 0 0 0 0 6 6 6 6 0 0 18 % N
% Pro: 12 36 12 42 0 6 6 12 12 0 0 0 6 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % Q
% Arg: 6 0 0 0 6 0 6 18 36 6 0 0 0 6 6 % R
% Ser: 0 6 0 0 12 0 12 42 0 12 6 6 6 12 12 % S
% Thr: 6 0 0 6 0 6 0 0 12 12 0 18 0 6 12 % T
% Val: 6 0 12 6 0 0 0 6 0 6 12 0 0 12 42 % V
% Trp: 6 6 0 0 6 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _