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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAD21
All Species:
32.73
Human Site:
S545
Identified Species:
55.38
UniProt:
O60216
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60216
NP_006256.1
631
71690
S545
E
E
E
D
E
D
A
S
G
G
D
Q
D
Q
E
Chimpanzee
Pan troglodytes
XP_001138624
622
70634
S536
E
E
E
D
E
D
A
S
G
G
D
Q
D
Q
E
Rhesus Macaque
Macaca mulatta
XP_001094435
631
71657
S545
E
E
E
D
E
D
A
S
G
G
D
Q
D
Q
E
Dog
Lupus familis
XP_539142
631
71617
S545
E
E
E
D
E
D
A
S
G
G
D
Q
D
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61550
635
72004
S549
E
E
E
D
E
D
A
S
G
G
D
Q
D
Q
E
Rat
Rattus norvegicus
NP_001020872
635
71973
S549
E
E
E
D
E
D
A
S
G
G
D
Q
D
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508586
708
79990
A548
E
E
E
E
E
D
A
A
G
G
D
Q
D
Q
E
Chicken
Gallus gallus
NP_001026121
633
72033
T547
E
E
E
E
E
D
G
T
G
G
D
Q
D
Q
E
Frog
Xenopus laevis
O93310
629
71536
T543
E
E
E
E
E
D
T
T
G
T
E
Q
D
Q
E
Zebra Danio
Brachydanio rerio
NP_001038585
637
71635
Q551
E
E
E
E
E
E
G
Q
S
G
D
Q
D
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015132
715
79926
M627
Q
N
H
G
D
E
Q
M
E
N
E
T
D
E
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780787
610
68191
E523
E
E
E
E
E
L
Q
E
G
E
D
Q
E
A
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FQ19
693
77123
Q604
P
V
G
T
P
A
S
Q
D
S
A
A
L
T
G
Baker's Yeast
Sacchar. cerevisiae
Q12158
566
63272
T476
Q
T
E
K
V
R
P
T
P
G
E
V
A
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.8
98.7
N.A.
97
97
N.A.
84.4
93
86.2
80.3
N.A.
38
N.A.
N.A.
46.9
Protein Similarity:
100
98.5
100
99.5
N.A.
98.4
98.4
N.A.
87.8
97
92.2
88.3
N.A.
54.4
N.A.
N.A.
61.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
80
66.6
66.6
N.A.
6.6
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
86.6
80
N.A.
46.6
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.2
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.9
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
50
8
0
0
8
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
43
8
65
0
0
8
0
72
0
79
0
0
% D
% Glu:
79
79
86
36
79
15
0
8
8
8
22
0
8
8
72
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
0
15
0
72
72
0
0
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
8
0
0
0
8
0
8
0
8
0
0
0
0
0
0
% P
% Gln:
15
0
0
0
0
0
15
15
0
0
0
79
0
72
8
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
43
8
8
0
0
0
8
0
% S
% Thr:
0
8
0
8
0
0
8
22
0
8
0
8
0
8
0
% T
% Val:
0
8
0
0
8
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _