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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAD21
All Species:
37.58
Human Site:
S280
Identified Species:
63.59
UniProt:
O60216
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60216
NP_006256.1
631
71690
S280
G
G
P
D
S
P
D
S
V
D
P
V
E
P
M
Chimpanzee
Pan troglodytes
XP_001138624
622
70634
S280
G
G
P
D
S
P
D
S
V
D
P
V
E
P
M
Rhesus Macaque
Macaca mulatta
XP_001094435
631
71657
S280
G
G
P
D
S
P
D
S
V
D
P
V
E
P
M
Dog
Lupus familis
XP_539142
631
71617
S280
G
G
P
D
S
P
D
S
V
D
P
V
E
P
M
Cat
Felis silvestris
Mouse
Mus musculus
Q61550
635
72004
S280
G
G
P
D
S
P
D
S
V
D
P
V
E
P
M
Rat
Rattus norvegicus
NP_001020872
635
71973
S280
G
G
P
D
S
P
D
S
V
D
P
V
E
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508586
708
79990
S280
G
G
P
D
S
P
D
S
V
D
P
V
E
P
L
Chicken
Gallus gallus
NP_001026121
633
72033
S279
G
G
P
D
S
P
D
S
V
D
P
V
E
P
L
Frog
Xenopus laevis
O93310
629
71536
S278
G
A
P
D
S
P
D
S
V
D
P
V
E
P
L
Zebra Danio
Brachydanio rerio
NP_001038585
637
71635
D281
A
G
G
P
D
S
P
D
S
G
P
V
E
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015132
715
79926
N289
E
K
E
E
N
N
L
N
G
H
A
S
V
S
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780787
610
68191
E286
Q
I
R
G
Q
P
M
E
Q
G
E
D
V
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FQ19
693
77123
T296
T
L
N
E
K
E
P
T
I
P
S
I
D
E
E
Baker's Yeast
Sacchar. cerevisiae
Q12158
566
63272
K290
G
F
D
L
D
I
E
K
E
A
P
A
G
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.8
98.7
N.A.
97
97
N.A.
84.4
93
86.2
80.3
N.A.
38
N.A.
N.A.
46.9
Protein Similarity:
100
98.5
100
99.5
N.A.
98.4
98.4
N.A.
87.8
97
92.2
88.3
N.A.
54.4
N.A.
N.A.
61.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
86.6
33.3
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
40
N.A.
20
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.2
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.9
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
0
8
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
65
15
0
65
8
0
65
0
8
8
0
0
% D
% Glu:
8
0
8
15
0
8
8
8
8
0
8
0
72
8
22
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
72
65
8
8
0
0
0
0
8
15
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
0
0
8
0
0
8
0
0
8
% I
% Lys:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
8
0
0
8
0
0
0
0
0
0
0
29
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
43
% M
% Asn:
0
0
8
0
8
8
0
8
0
0
0
0
0
8
0
% N
% Pro:
0
0
65
8
0
72
15
0
0
8
79
0
0
72
0
% P
% Gln:
8
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
65
8
0
65
8
0
8
8
0
8
0
% S
% Thr:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
65
0
0
72
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _