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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX1
All Species:
29.39
Human Site:
S573
Identified Species:
40.42
UniProt:
O43933
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43933
NP_000457.1
1283
142867
S573
S
L
E
H
I
T
H
S
L
L
G
R
P
L
S
Chimpanzee
Pan troglodytes
XP_519198
1283
142803
S573
S
L
E
H
I
T
H
S
L
L
G
R
P
L
S
Rhesus Macaque
Macaca mulatta
XP_001101055
1278
142022
S571
S
L
E
H
I
T
H
S
L
L
G
R
P
L
S
Dog
Lupus familis
XP_532459
1267
140567
S557
S
L
E
H
I
T
H
S
L
L
G
R
P
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5BL07
1284
141409
S574
A
M
E
H
I
T
H
S
L
L
G
R
P
L
S
Rat
Rattus norvegicus
P46462
806
89330
T180
Y
C
I
V
A
P
D
T
V
I
H
C
E
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520628
1178
126535
D538
D
L
G
A
T
L
L
D
H
I
T
H
S
L
L
Chicken
Gallus gallus
XP_418655
1290
143066
S581
S
F
E
H
I
S
H
S
L
L
G
R
P
L
S
Frog
Xenopus laevis
P23787
805
89193
D179
P
Y
C
I
V
A
P
D
T
V
I
H
C
E
G
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
T180
Y
C
I
V
A
P
D
T
V
I
H
C
E
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
P175
E
P
Y
C
I
V
A
P
E
T
V
I
F
C
D
Honey Bee
Apis mellifera
XP_397107
1069
120490
V443
L
R
D
T
K
V
R
V
R
S
V
E
E
K
D
Nematode Worm
Caenorhab. elegans
P54812
810
89622
D184
P
A
C
I
V
A
P
D
T
V
I
H
Y
E
G
Sea Urchin
Strong. purpuratus
XP_797089
1508
166130
T727
A
L
E
H
I
T
A
T
L
T
S
R
P
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCN8
815
90322
C189
A
P
D
T
E
I
F
C
E
G
E
P
I
K
R
Baker's Yeast
Sacchar. cerevisiae
P24004
1043
117258
V417
H
L
P
K
H
Y
H
V
K
E
T
G
E
V
S
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
T623
V
L
G
L
I
A
A
T
R
P
G
Q
S
L
H
Conservation
Percent
Protein Identity:
100
99.6
92.8
86.4
N.A.
82
23.3
N.A.
52.4
62.4
22.9
22.8
N.A.
23.6
27.6
22.1
35.2
Protein Similarity:
100
100
94.9
92
N.A.
89.5
39.2
N.A.
66
77.6
38.6
39
N.A.
37.6
46.7
38.4
53.2
P-Site Identity:
100
100
100
100
N.A.
86.6
0
N.A.
13.3
86.6
0
0
N.A.
6.6
0
0
60
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
20
93.3
13.3
20
N.A.
6.6
6.6
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.7
21.4
Protein Similarity:
N.A.
N.A.
N.A.
38.5
45.2
40.9
P-Site Identity:
N.A.
N.A.
N.A.
0
20
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
6
0
6
12
18
18
0
0
0
0
0
0
0
0
% A
% Cys:
0
12
12
6
0
0
0
6
0
0
0
12
6
6
0
% C
% Asp:
6
0
12
0
0
0
12
18
0
0
0
0
0
0
12
% D
% Glu:
6
0
42
0
6
0
0
0
12
6
6
6
24
12
12
% E
% Phe:
0
6
0
0
0
0
6
0
0
0
0
0
6
0
0
% F
% Gly:
0
0
12
0
0
0
0
0
0
6
42
6
0
12
18
% G
% His:
6
0
0
42
6
0
42
0
6
0
12
18
0
0
6
% H
% Ile:
0
0
12
12
53
6
0
0
0
18
12
6
6
0
0
% I
% Lys:
0
0
0
6
6
0
0
0
6
0
0
0
0
12
0
% K
% Leu:
6
48
0
6
0
6
6
0
42
36
0
0
0
53
6
% L
% Met:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
12
6
0
0
12
12
6
0
6
0
6
42
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% Q
% Arg:
0
6
0
0
0
0
6
0
12
0
0
42
0
0
6
% R
% Ser:
30
0
0
0
0
6
0
36
0
6
6
0
12
0
42
% S
% Thr:
0
0
0
12
6
36
0
24
12
12
12
0
0
0
0
% T
% Val:
6
0
0
12
12
12
0
12
12
12
12
0
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
6
6
0
0
6
0
0
0
0
0
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _