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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFNA2
All Species:
17.27
Human Site:
T186
Identified Species:
42.22
UniProt:
O43921
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43921
NP_001396.2
213
23878
T186
E
A
P
E
P
I
F
T
S
N
N
S
C
S
S
Chimpanzee
Pan troglodytes
XP_001172483
296
32091
T269
E
A
P
E
P
I
F
T
S
N
N
S
C
S
S
Rhesus Macaque
Macaca mulatta
XP_001117318
695
73967
T668
E
P
P
E
P
I
F
T
S
N
N
S
C
S
S
Dog
Lupus familis
XP_850582
333
37868
V279
T
I
G
V
H
D
R
V
F
D
V
N
D
K
V
Cat
Felis silvestris
Mouse
Mus musculus
P52801
209
23567
T182
E
A
P
E
P
I
F
T
S
N
S
S
C
S
G
Rat
Rattus norvegicus
P97605
228
26340
V174
T
I
G
V
R
D
R
V
F
D
V
N
D
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513524
228
26309
V174
T
I
G
V
H
D
R
V
F
D
V
N
D
K
V
Chicken
Gallus gallus
P52802
200
23031
T173
E
S
P
E
P
I
F
T
S
N
N
S
C
C
S
Frog
Xenopus laevis
P52794
216
24737
H174
N
V
H
T
P
R
S
H
I
Q
S
D
E
P
E
Zebra Danio
Brachydanio rerio
P79727
195
22669
D169
S
P
E
P
F
L
T
D
Q
S
Q
R
C
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.4
29.5
30.9
N.A.
89.1
46.9
N.A.
45.6
70.8
40.2
53
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
64.1
30.2
44.4
N.A.
92
65.3
N.A.
64.9
77.4
56
68.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
86.6
0
N.A.
0
86.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
13.3
N.A.
93.3
13.3
N.A.
13.3
93.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
0
0
0
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
60
10
0
% C
% Asp:
0
0
0
0
0
30
0
10
0
30
0
10
30
0
0
% D
% Glu:
50
0
10
50
0
0
0
0
0
0
0
0
10
0
10
% E
% Phe:
0
0
0
0
10
0
50
0
30
0
0
0
0
0
0
% F
% Gly:
0
0
30
0
0
0
0
0
0
0
0
0
0
10
10
% G
% His:
0
0
10
0
20
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
30
0
0
0
50
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
50
40
30
0
0
0
% N
% Pro:
0
20
50
10
60
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
10
10
0
0
0
0
% Q
% Arg:
0
0
0
0
10
10
30
0
0
0
0
10
0
0
0
% R
% Ser:
10
10
0
0
0
0
10
0
50
10
20
50
0
40
40
% S
% Thr:
30
0
0
10
0
0
10
50
0
0
0
0
0
0
0
% T
% Val:
0
10
0
30
0
0
0
30
0
0
30
0
0
0
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _