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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXTL3
All Species:
9.09
Human Site:
Y261
Identified Species:
15.38
UniProt:
O43909
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43909
NP_001431.1
919
104749
Y261
A
E
L
E
K
Q
L
Y
S
L
P
H
W
R
T
Chimpanzee
Pan troglodytes
XP_001166624
919
104712
Y261
A
E
L
E
K
Q
L
Y
S
L
P
H
W
R
T
Rhesus Macaque
Macaca mulatta
XP_001111377
724
82688
A116
K
L
N
L
K
I
E
A
C
K
K
S
I
E
N
Dog
Lupus familis
XP_850237
919
104592
Y261
A
E
L
E
K
Q
L
Y
S
L
P
H
W
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL6
918
104529
F261
A
D
L
E
K
Q
L
F
S
L
P
H
W
R
T
Rat
Rattus norvegicus
NP_064482
919
104425
H261
A
D
L
E
K
Q
L
H
S
L
P
H
W
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505771
333
35563
Chicken
Gallus gallus
XP_420030
919
105127
H261
T
E
L
E
Q
Q
L
H
S
L
P
Y
W
R
T
Frog
Xenopus laevis
NP_001085848
919
105285
H261
T
E
L
E
E
Q
L
H
S
L
P
Y
W
R
T
Zebra Danio
Brachydanio rerio
Q5IGR7
741
85103
I133
Y
Q
N
I
L
S
T
I
E
G
S
R
F
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZ08
972
110981
H301
Y
A
A
Q
E
A
E
H
Q
Q
P
S
T
P
T
Honey Bee
Apis mellifera
XP_397082
948
108470
P282
V
K
K
L
H
A
L
P
Y
W
G
G
D
G
R
Nematode Worm
Caenorhab. elegans
O01705
814
94178
L206
F
Q
E
V
I
P
N
L
V
E
T
P
D
K
A
Sea Urchin
Strong. purpuratus
XP_790713
948
109252
H285
H
E
L
E
V
G
L
H
K
L
P
Y
W
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
78.5
98.4
N.A.
96.9
97.2
N.A.
29.8
90.8
87.6
27.4
N.A.
48.4
48.6
33.5
50.6
Protein Similarity:
100
99.8
78.5
99
N.A.
97.7
98.2
N.A.
32.4
96.1
95
44.5
N.A.
64.9
66.8
51.6
69.8
P-Site Identity:
100
100
6.6
100
N.A.
86.6
86.6
N.A.
0
73.3
73.3
6.6
N.A.
13.3
6.6
0
53.3
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
0
93.3
93.3
20
N.A.
33.3
13.3
13.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
8
8
0
0
15
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
0
0
0
0
0
0
0
0
15
0
0
% D
% Glu:
0
43
8
58
15
0
15
0
8
8
0
0
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
8
8
8
0
8
0
% G
% His:
8
0
0
0
8
0
0
36
0
0
0
36
0
0
8
% H
% Ile:
0
0
0
8
8
8
0
8
0
0
0
0
8
0
0
% I
% Lys:
8
8
8
0
43
0
0
0
8
8
8
0
0
8
0
% K
% Leu:
0
8
58
15
8
0
65
8
0
58
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
0
0
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
8
0
8
0
0
65
8
0
8
0
% P
% Gln:
0
15
0
8
8
50
0
0
8
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
0
58
8
% R
% Ser:
0
0
0
0
0
8
0
0
50
0
8
15
0
0
0
% S
% Thr:
15
0
0
0
0
0
8
0
0
0
8
0
8
0
65
% T
% Val:
8
0
0
8
8
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
58
0
0
% W
% Tyr:
15
0
0
0
0
0
0
22
8
0
0
22
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _