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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXTL3
All Species:
30.3
Human Site:
T518
Identified Species:
51.28
UniProt:
O43909
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43909
NP_001431.1
919
104749
T518
Q
G
R
F
L
W
E
T
Y
F
S
T
A
D
S
Chimpanzee
Pan troglodytes
XP_001166624
919
104712
T518
Q
G
R
F
L
W
E
T
Y
F
S
T
A
D
S
Rhesus Macaque
Macaca mulatta
XP_001111377
724
82688
A356
P
I
R
E
E
A
A
A
E
I
P
H
R
S
G
Dog
Lupus familis
XP_850237
919
104592
T518
Q
G
R
F
L
W
E
T
Y
F
S
T
A
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL6
918
104529
T517
Q
G
R
F
L
W
E
T
Y
F
S
T
A
D
S
Rat
Rattus norvegicus
NP_064482
919
104425
T518
Q
G
R
F
L
W
E
T
Y
F
S
T
A
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505771
333
35563
Chicken
Gallus gallus
XP_420030
919
105127
T518
Q
G
R
F
L
W
E
T
Y
F
S
T
S
D
N
Frog
Xenopus laevis
NP_001085848
919
105285
T518
Q
G
R
F
L
W
E
T
Y
F
S
T
S
D
T
Zebra Danio
Brachydanio rerio
Q5IGR7
741
85103
A373
V
I
D
W
N
T
A
A
V
I
G
D
E
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZ08
972
110981
R569
Q
G
R
L
I
W
E
R
Y
L
S
S
V
Q
A
Honey Bee
Apis mellifera
XP_397082
948
108470
H547
Q
G
R
L
I
W
E
H
Y
L
S
T
A
Q
G
Nematode Worm
Caenorhab. elegans
O01705
814
94178
R446
I
P
T
R
E
V
R
R
N
Q
A
I
P
L
F
Sea Urchin
Strong. purpuratus
XP_790713
948
109252
T547
Q
G
W
F
L
W
T
T
Y
L
S
N
T
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
78.5
98.4
N.A.
96.9
97.2
N.A.
29.8
90.8
87.6
27.4
N.A.
48.4
48.6
33.5
50.6
Protein Similarity:
100
99.8
78.5
99
N.A.
97.7
98.2
N.A.
32.4
96.1
95
44.5
N.A.
64.9
66.8
51.6
69.8
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
0
86.6
86.6
0
N.A.
46.6
60
0
60
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
0
100
100
6.6
N.A.
66.6
66.6
6.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
15
15
0
0
8
0
43
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
8
0
58
0
% D
% Glu:
0
0
0
8
15
0
65
0
8
0
0
0
8
0
0
% E
% Phe:
0
0
0
58
0
0
0
0
0
50
0
0
0
0
8
% F
% Gly:
0
72
0
0
0
0
0
0
0
0
8
0
0
0
15
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% H
% Ile:
8
15
0
0
15
0
0
0
0
15
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
15
58
0
0
0
0
22
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
8
0
0
8
0
0
8
% N
% Pro:
8
8
0
0
0
0
0
0
0
0
8
0
8
0
0
% P
% Gln:
72
0
0
0
0
0
0
0
0
8
0
0
0
15
0
% Q
% Arg:
0
0
72
8
0
0
8
15
0
0
0
0
8
8
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
72
8
15
8
36
% S
% Thr:
0
0
8
0
0
8
8
58
0
0
0
58
8
0
8
% T
% Val:
8
0
0
0
0
8
0
0
8
0
0
0
8
0
0
% V
% Trp:
0
0
8
8
0
72
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
72
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _