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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXTL3
All Species:
31.21
Human Site:
S499
Identified Species:
52.82
UniProt:
O43909
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43909
NP_001431.1
919
104749
S499
E
V
H
F
L
L
R
S
L
S
D
S
D
L
L
Chimpanzee
Pan troglodytes
XP_001166624
919
104712
S499
E
V
H
F
L
L
R
S
L
S
D
S
D
L
L
Rhesus Macaque
Macaca mulatta
XP_001111377
724
82688
A337
S
I
F
N
T
V
L
A
M
I
R
T
R
I
Q
Dog
Lupus familis
XP_850237
919
104592
S499
E
V
H
F
L
L
R
S
L
S
D
S
D
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL6
918
104529
S498
E
V
H
F
L
L
R
S
L
S
D
S
D
L
L
Rat
Rattus norvegicus
NP_064482
919
104425
S499
E
V
H
F
L
L
R
S
L
S
D
S
D
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505771
333
35563
Chicken
Gallus gallus
XP_420030
919
105127
S499
E
V
H
F
L
L
R
S
I
S
D
N
D
L
L
Frog
Xenopus laevis
NP_001085848
919
105285
S499
E
V
H
F
L
L
R
S
L
S
D
N
D
L
L
Zebra Danio
Brachydanio rerio
Q5IGR7
741
85103
M354
Q
A
A
C
V
P
V
M
L
S
N
G
W
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZ08
972
110981
A550
E
L
H
F
L
L
R
A
V
Q
D
A
D
L
L
Honey Bee
Apis mellifera
XP_397082
948
108470
A528
E
M
H
F
L
L
R
A
V
L
D
T
D
L
L
Nematode Worm
Caenorhab. elegans
O01705
814
94178
R427
A
D
R
H
L
L
A
R
S
L
L
A
A
L
R
Sea Urchin
Strong. purpuratus
XP_790713
948
109252
T528
E
L
Y
F
Y
L
K
T
I
Q
D
N
D
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
78.5
98.4
N.A.
96.9
97.2
N.A.
29.8
90.8
87.6
27.4
N.A.
48.4
48.6
33.5
50.6
Protein Similarity:
100
99.8
78.5
99
N.A.
97.7
98.2
N.A.
32.4
96.1
95
44.5
N.A.
64.9
66.8
51.6
69.8
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
0
86.6
93.3
20
N.A.
66.6
66.6
20
40
P-Site Similarity:
100
100
40
100
N.A.
100
100
N.A.
0
100
100
40
N.A.
93.3
93.3
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
0
8
22
0
0
0
15
8
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
72
0
72
0
0
% D
% Glu:
72
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
8
72
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
65
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
15
8
0
0
0
15
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
15
0
0
72
79
8
0
50
15
8
0
0
72
79
% L
% Met:
0
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
8
22
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
15
0
0
0
0
8
% Q
% Arg:
0
0
8
0
0
0
65
8
0
0
8
0
8
0
8
% R
% Ser:
8
0
0
0
0
0
0
50
8
58
0
36
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
8
0
0
0
15
0
0
0
% T
% Val:
0
50
0
0
8
8
8
0
15
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _