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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLL1
All Species:
48.79
Human Site:
S870
Identified Species:
82.56
UniProt:
O43897
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43897
NP_036596.3
1013
114709
S870
K
M
F
V
R
F
V
S
D
A
S
V
Q
R
K
Chimpanzee
Pan troglodytes
XP_001150703
1013
114731
S870
K
M
F
V
R
F
V
S
D
A
S
V
Q
R
K
Rhesus Macaque
Macaca mulatta
XP_001101883
1013
114718
S870
K
M
F
V
R
F
V
S
D
A
S
V
Q
R
K
Dog
Lupus familis
XP_539791
1045
118180
S902
K
M
F
V
R
F
I
S
D
A
S
V
Q
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q62381
1013
114514
S870
E
M
F
I
R
F
I
S
D
A
S
V
Q
R
K
Rat
Rattus norvegicus
NP_001099551
1013
114567
S870
E
M
F
I
R
F
I
S
D
A
S
V
Q
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509196
1014
114574
S871
K
M
F
L
R
F
V
S
D
A
S
V
Q
R
K
Chicken
Gallus gallus
Q9DER7
1008
114873
S865
K
M
F
L
R
F
I
S
D
A
S
V
Q
R
K
Frog
Xenopus laevis
Q8JI28
1007
114347
S865
E
M
F
I
R
F
V
S
D
A
S
V
Q
R
K
Zebra Danio
Brachydanio rerio
O57460
1022
115518
S879
K
M
Y
L
R
F
I
S
D
A
S
V
Q
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25723
1067
121762
T893
E
M
F
M
V
L
A
T
D
A
G
L
Q
R
K
Honey Bee
Apis mellifera
XP_393866
1225
138704
S1070
Q
M
Y
M
V
F
K
S
D
A
S
V
Q
R
K
Nematode Worm
Caenorhab. elegans
Q20176
951
107516
L809
T
S
L
C
G
G
R
L
T
A
E
S
T
P
G
Sea Urchin
Strong. purpuratus
P98069
639
71875
Y497
L
I
G
R
Y
C
G
Y
F
I
P
D
D
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.1
89.9
N.A.
93.5
93.5
N.A.
89.2
88.1
85.2
81.1
N.A.
41.5
45
42.5
38.3
Protein Similarity:
100
100
99.6
92.6
N.A.
96.4
96.3
N.A.
94.2
93.9
92.9
90.9
N.A.
59
60
59.2
48.5
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
93.3
86.6
86.6
80
N.A.
46.6
66.6
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
73.3
86.6
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
93
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
86
0
0
8
8
0
0
% D
% Glu:
29
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
72
0
0
79
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
8
8
0
0
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
22
0
0
36
0
0
8
0
0
0
8
0
% I
% Lys:
50
0
0
0
0
0
8
0
0
0
0
0
0
0
93
% K
% Leu:
8
0
8
22
0
8
0
8
0
0
0
8
0
0
0
% L
% Met:
0
86
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
86
0
0
% Q
% Arg:
0
0
0
8
72
0
8
0
0
0
0
0
0
86
0
% R
% Ser:
0
8
0
0
0
0
0
79
0
0
79
8
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
8
8
0
0
0
8
0
0
% T
% Val:
0
0
0
29
15
0
36
0
0
0
0
79
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
0
8
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _