KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinector
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF1C
All Species:
28.79
Human Site:
S290
Identified Species:
45.24
UniProt:
O43896
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43896
NP_006603.2
1103
122947
S290
S
A
L
A
D
M
Q
S
K
K
R
K
S
D
F
Chimpanzee
Pan troglodytes
XP_511296
1097
122335
S290
S
A
L
A
D
M
Q
S
K
K
R
K
S
D
F
Rhesus Macaque
Macaca mulatta
XP_001117788
1214
134234
S401
S
A
L
A
D
M
Q
S
K
K
R
K
S
D
F
Dog
Lupus familis
XP_546571
1191
131317
S377
S
A
L
A
D
L
Q
S
K
K
R
K
S
D
F
Cat
Felis silvestris
Mouse
Mus musculus
O35071
1100
122416
S290
S
A
L
A
D
L
Q
S
K
K
R
K
S
D
F
Rat
Rattus norvegicus
O35787
1097
122315
S289
S
A
L
A
D
L
Q
S
K
K
R
K
S
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509769
1770
199343
K290
S
A
L
A
E
V
S
K
K
K
K
K
T
D
F
Chicken
Gallus gallus
XP_417608
1757
197902
K290
S
A
L
A
E
V
S
K
K
K
K
K
T
D
F
Frog
Xenopus laevis
Q91784
1226
138905
K340
R
A
R
K
I
K
N
K
P
I
V
N
T
D
P
Zebra Danio
Brachydanio rerio
XP_699380
1180
133432
S291
A
L
A
D
M
H
G
S
K
K
R
R
S
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZAJ2
1670
189326
K293
A
E
V
A
S
K
K
K
N
T
K
K
A
D
F
Honey Bee
Apis mellifera
XP_397276
1682
191012
K291
A
L
A
E
I
A
T
K
K
K
K
K
A
D
F
Nematode Worm
Caenorhab. elegans
P23678
1584
179603
T287
S
K
L
A
E
E
S
T
K
K
K
K
S
N
K
Sea Urchin
Strong. purpuratus
P46872
699
78679
Q43
D
E
M
R
G
T
V
Q
V
T
N
P
N
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
L272
L
G
M
V
I
N
A
L
T
D
G
K
S
S
H
Conservation
Percent
Protein Identity:
100
99
89.6
87.7
N.A.
94.1
92.7
N.A.
38.1
38.7
23.9
60.4
N.A.
30.7
36.2
30.3
27.6
Protein Similarity:
100
99
89.9
89.3
N.A.
95.5
94.6
N.A.
48.6
48.4
42.3
71.8
N.A.
42.8
47.6
43.5
41
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
60
60
13.3
46.6
N.A.
26.6
33.3
46.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
86.6
20
60
N.A.
60
53.3
73.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
60
14
67
0
7
7
0
0
0
0
0
14
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
40
0
0
0
0
7
0
0
0
80
0
% D
% Glu:
0
14
0
7
20
7
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
74
% F
% Gly:
0
7
0
0
7
0
7
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
20
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
7
0
7
0
14
7
34
74
74
34
80
0
0
7
% K
% Leu:
7
14
60
0
0
20
0
7
0
0
0
0
0
0
0
% L
% Met:
0
0
14
0
7
20
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
7
0
7
0
7
7
7
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
14
% P
% Gln:
0
0
0
0
0
0
40
7
0
0
0
0
0
0
0
% Q
% Arg:
7
0
7
7
0
0
0
0
0
0
47
7
0
0
0
% R
% Ser:
60
0
0
0
7
0
20
47
0
0
0
0
60
7
0
% S
% Thr:
0
0
0
0
0
7
7
7
7
14
0
0
20
0
0
% T
% Val:
0
0
7
7
0
14
7
0
7
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _