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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPNPEP2
All Species:
27.27
Human Site:
Y518
Identified Species:
50
UniProt:
O43895
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43895
NP_003390.4
674
75625
Y518
L
W
D
A
G
L
N
Y
G
H
G
T
G
H
G
Chimpanzee
Pan troglodytes
XP_521256
675
75579
Y519
L
W
D
A
G
L
N
Y
G
H
G
T
G
H
G
Rhesus Macaque
Macaca mulatta
XP_001091201
674
75480
Y518
L
W
D
A
G
L
N
Y
G
H
G
T
G
H
G
Dog
Lupus familis
XP_549245
890
99571
Y732
L
W
D
V
G
L
N
Y
G
H
G
T
G
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1B1
623
69573
T487
G
L
D
Y
L
H
G
T
G
H
G
V
G
S
F
Rat
Rattus norvegicus
O54975
623
69639
T487
G
L
D
Y
L
H
G
T
G
H
G
V
G
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521654
589
66878
N453
T
H
R
M
L
S
H
N
E
M
Y
L
L
D
S
Chicken
Gallus gallus
XP_421751
623
69997
T487
G
L
D
Y
L
H
G
T
G
H
G
V
G
S
F
Frog
Xenopus laevis
NP_001084745
621
69004
T485
G
L
D
Y
L
H
G
T
G
H
G
V
G
S
F
Zebra Danio
Brachydanio rerio
NP_957326
702
79242
Y544
L
W
E
V
G
L
N
Y
G
H
G
T
G
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477409
613
68487
G477
W
D
V
G
L
D
Y
G
H
G
T
G
H
G
V
Honey Bee
Apis mellifera
XP_392697
724
82990
Y537
L
W
N
I
G
Y
D
Y
L
H
G
T
G
H
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07825
749
84906
A589
L
V
L
K
G
G
L
A
L
E
R
L
I
F
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
98
63.1
N.A.
40.2
39.6
N.A.
59
41
41
54.7
N.A.
39.3
36.1
N.A.
N.A.
Protein Similarity:
100
96.8
98.9
68.3
N.A.
58.6
58.1
N.A.
68.4
58.9
60.2
68.9
N.A.
57.4
54.7
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
33.3
33.3
N.A.
0
33.3
33.3
86.6
N.A.
0
66.6
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
33.3
33.3
N.A.
6.6
33.3
33.3
93.3
N.A.
0
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
24
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
62
0
0
8
8
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
31
% F
% Gly:
31
0
0
8
54
8
31
8
70
8
77
8
77
8
47
% G
% His:
0
8
0
0
0
31
8
0
8
77
0
0
8
47
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
54
31
8
0
47
39
8
0
16
0
0
16
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
39
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
0
0
0
0
0
0
31
8
% S
% Thr:
8
0
0
0
0
0
0
31
0
0
8
47
0
0
0
% T
% Val:
0
8
8
16
0
0
0
0
0
0
0
31
0
0
8
% V
% Trp:
8
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
31
0
8
8
47
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _