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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPNPEP2
All Species:
13.03
Human Site:
Y205
Identified Species:
23.89
UniProt:
O43895
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43895
NP_003390.4
674
75625
Y205
P
V
P
N
Q
P
I
Y
A
L
Q
E
A
F
T
Chimpanzee
Pan troglodytes
XP_521256
675
75579
Y205
P
V
P
N
Q
P
I
Y
A
L
Q
E
A
F
T
Rhesus Macaque
Macaca mulatta
XP_001091201
674
75480
Y205
P
V
P
N
Q
P
I
Y
A
L
Q
E
A
F
T
Dog
Lupus familis
XP_549245
890
99571
Y419
L
F
P
S
Q
P
I
Y
A
L
K
E
A
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1B1
623
69573
W178
L
D
Y
T
G
I
S
W
K
E
K
V
A
D
L
Rat
Rattus norvegicus
O54975
623
69639
W178
L
D
Y
T
G
I
S
W
K
E
K
V
A
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521654
589
66878
V144
N
W
Q
L
L
Q
S
V
D
I
S
S
I
L
S
Chicken
Gallus gallus
XP_421751
623
69997
W178
L
S
Y
T
G
V
S
W
R
D
K
I
V
A
L
Frog
Xenopus laevis
NP_001084745
621
69004
W176
L
N
Y
T
G
L
S
W
K
A
K
I
E
S
L
Zebra Danio
Brachydanio rerio
NP_957326
702
79242
R231
L
P
P
D
N
P
T
R
L
P
D
S
V
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477409
613
68487
I168
P
Q
T
S
N
K
I
I
T
L
K
L
E
H
S
Honey Bee
Apis mellifera
XP_392697
724
82990
K224
P
A
Y
P
L
P
D
K
Y
S
G
R
A
W
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07825
749
84906
E279
D
S
I
W
P
D
F
E
T
L
P
E
R
P
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
98
63.1
N.A.
40.2
39.6
N.A.
59
41
41
54.7
N.A.
39.3
36.1
N.A.
N.A.
Protein Similarity:
100
96.8
98.9
68.3
N.A.
58.6
58.1
N.A.
68.4
58.9
60.2
68.9
N.A.
57.4
54.7
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
6.6
6.6
N.A.
0
0
0
13.3
N.A.
20
20
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
20
20
N.A.
13.3
13.3
13.3
20
N.A.
40
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
31
8
0
0
54
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
16
0
8
0
8
8
0
8
8
8
0
0
16
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
16
0
39
16
0
8
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
0
0
0
31
0
% F
% Gly:
0
0
0
0
31
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
16
39
8
0
8
0
16
8
8
0
% I
% Lys:
0
0
0
0
0
8
0
8
24
0
47
0
0
0
0
% K
% Leu:
47
0
0
8
16
8
0
0
8
47
0
8
0
8
31
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
24
16
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
39
8
39
8
8
47
0
0
0
8
8
0
0
8
0
% P
% Gln:
0
8
8
0
31
8
0
0
0
0
24
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
8
8
0
0
8
8
0
0
% R
% Ser:
0
16
0
16
0
0
39
0
0
8
8
16
0
8
16
% S
% Thr:
0
0
8
31
0
0
8
0
16
0
0
0
0
0
31
% T
% Val:
0
24
0
0
0
8
0
8
0
0
0
16
16
0
0
% V
% Trp:
0
8
0
8
0
0
0
31
0
0
0
0
0
8
0
% W
% Tyr:
0
0
39
0
0
0
0
31
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _