KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPNPEP2
All Species:
13.94
Human Site:
T470
Identified Species:
25.56
UniProt:
O43895
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43895
NP_003390.4
674
75625
T470
T
R
T
V
H
W
G
T
P
S
A
F
Q
K
E
Chimpanzee
Pan troglodytes
XP_521256
675
75579
G470
I
T
R
T
V
H
W
G
T
P
S
A
F
Q
K
Rhesus Macaque
Macaca mulatta
XP_001091201
674
75480
T470
T
R
T
V
H
W
G
T
P
S
A
F
Q
K
E
Dog
Lupus familis
XP_549245
890
99571
T684
T
R
T
V
H
W
G
T
P
S
A
F
Q
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1B1
623
69573
C443
P
T
A
Y
E
K
E
C
F
T
Y
V
L
K
G
Rat
Rattus norvegicus
O54975
623
69639
C443
P
T
A
Y
E
K
E
C
F
T
Y
V
L
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521654
589
66878
Y409
N
E
F
S
G
A
V
Y
V
D
Q
L
R
R
E
Chicken
Gallus gallus
XP_421751
623
69997
C443
P
S
A
Y
E
K
E
C
F
T
C
V
L
K
G
Frog
Xenopus laevis
NP_001084745
621
69004
C441
P
T
D
Y
E
K
E
C
F
T
Y
V
L
Q
G
Zebra Danio
Brachydanio rerio
NP_957326
702
79242
K496
T
R
T
V
H
W
G
K
P
T
D
F
Q
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477409
613
68487
Q433
F
G
E
P
T
E
F
Q
K
E
A
Y
T
R
V
Honey Bee
Apis mellifera
XP_392697
724
82990
T489
T
R
T
L
H
F
G
T
P
T
E
E
Q
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07825
749
84906
P544
E
N
S
S
M
I
D
P
T
K
I
Y
L
C
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
98
63.1
N.A.
40.2
39.6
N.A.
59
41
41
54.7
N.A.
39.3
36.1
N.A.
N.A.
Protein Similarity:
100
96.8
98.9
68.3
N.A.
58.6
58.1
N.A.
68.4
58.9
60.2
68.9
N.A.
57.4
54.7
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
6.6
6.6
N.A.
6.6
6.6
0
80
N.A.
6.6
60
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
13.3
13.3
N.A.
20
13.3
13.3
86.6
N.A.
20
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
0
0
8
0
0
0
0
31
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
31
0
0
8
0
0
8
0
% C
% Asp:
0
0
8
0
0
0
8
0
0
8
8
0
0
0
8
% D
% Glu:
8
8
8
0
31
8
31
0
0
8
8
8
0
0
39
% E
% Phe:
8
0
8
0
0
8
8
0
31
0
0
31
8
0
0
% F
% Gly:
0
8
0
0
8
0
39
8
0
0
0
0
0
0
31
% G
% His:
0
0
0
0
39
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
31
0
8
8
8
0
0
0
62
16
% K
% Leu:
0
0
0
8
0
0
0
0
0
0
0
8
39
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
31
0
0
8
0
0
0
8
39
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
8
0
39
16
0
% Q
% Arg:
0
39
8
0
0
0
0
0
0
0
0
0
8
16
0
% R
% Ser:
0
8
8
16
0
0
0
0
0
24
8
0
0
0
0
% S
% Thr:
39
31
39
8
8
0
0
31
16
47
0
0
8
0
0
% T
% Val:
0
0
0
31
8
0
8
0
8
0
0
31
0
0
8
% V
% Trp:
0
0
0
0
0
31
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
31
0
0
0
8
0
0
24
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _