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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPNPEP2
All Species:
14.55
Human Site:
S443
Identified Species:
26.67
UniProt:
O43895
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43895
NP_003390.4
674
75625
S443
E
L
N
R
K
L
S
S
D
E
M
Y
L
L
D
Chimpanzee
Pan troglodytes
XP_521256
675
75579
S443
K
E
L
N
R
K
L
S
S
D
E
M
Y
L
L
Rhesus Macaque
Macaca mulatta
XP_001091201
674
75480
S443
E
L
N
R
K
L
S
S
D
E
M
Y
L
L
D
Dog
Lupus familis
XP_549245
890
99571
S657
E
Q
H
R
K
L
S
S
D
E
M
Y
L
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1B1
623
69573
S416
D
E
V
Y
L
I
D
S
G
A
Q
Y
K
D
G
Rat
Rattus norvegicus
O54975
623
69639
S416
D
E
V
Y
L
I
D
S
G
A
Q
Y
K
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521654
589
66878
A382
R
A
A
H
V
R
D
A
V
A
V
I
R
Y
L
Chicken
Gallus gallus
XP_421751
623
69997
S416
N
E
I
Y
L
L
D
S
G
A
Q
Y
K
D
G
Frog
Xenopus laevis
NP_001084745
621
69004
S414
N
E
I
F
L
L
D
S
G
A
Q
F
K
D
G
Zebra Danio
Brachydanio rerio
NP_957326
702
79242
V469
D
T
A
R
K
L
T
V
D
E
M
Y
L
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477409
613
68487
L406
I
N
D
K
E
I
Y
L
C
D
S
G
A
Q
Y
Honey Bee
Apis mellifera
XP_392697
724
82990
R462
L
T
N
I
K
I
G
R
T
S
T
L
V
V
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07825
749
84906
F517
R
N
F
M
G
N
S
F
E
T
I
S
S
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
98
63.1
N.A.
40.2
39.6
N.A.
59
41
41
54.7
N.A.
39.3
36.1
N.A.
N.A.
Protein Similarity:
100
96.8
98.9
68.3
N.A.
58.6
58.1
N.A.
68.4
58.9
60.2
68.9
N.A.
57.4
54.7
N.A.
N.A.
P-Site Identity:
100
13.3
100
86.6
N.A.
13.3
13.3
N.A.
0
20
13.3
60
N.A.
0
20
N.A.
N.A.
P-Site Similarity:
100
33.3
100
93.3
N.A.
26.6
26.6
N.A.
13.3
20
20
80
N.A.
33.3
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
0
0
0
0
8
0
39
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
24
0
8
0
0
0
39
0
31
16
0
0
0
31
39
% D
% Glu:
24
39
0
0
8
0
0
0
8
31
8
0
0
0
0
% E
% Phe:
0
0
8
8
0
0
0
8
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
8
0
8
0
31
0
0
8
0
0
39
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
16
8
0
31
0
0
0
0
8
8
0
0
0
% I
% Lys:
8
0
0
8
39
8
0
0
0
0
0
0
31
0
0
% K
% Leu:
8
16
8
0
31
47
8
8
0
0
0
8
31
31
16
% L
% Met:
0
0
0
8
0
0
0
0
0
0
31
8
0
0
0
% M
% Asn:
16
16
24
8
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
31
0
0
8
0
% Q
% Arg:
16
0
0
31
8
8
0
8
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
0
0
31
62
8
8
8
8
8
0
0
% S
% Thr:
0
16
0
0
0
0
8
0
8
8
8
0
0
8
0
% T
% Val:
0
0
16
0
8
0
0
8
8
0
8
0
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
24
0
0
8
0
0
0
0
54
8
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _