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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPNPEP2
All Species:
18.48
Human Site:
S422
Identified Species:
33.89
UniProt:
O43895
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43895
NP_003390.4
674
75625
S422
S
F
E
T
I
S
A
S
G
L
N
A
A
L
A
Chimpanzee
Pan troglodytes
XP_521256
675
75579
A422
P
S
F
E
T
I
S
A
S
G
L
N
A
A
L
Rhesus Macaque
Macaca mulatta
XP_001091201
674
75480
S422
S
F
E
T
I
S
A
S
G
L
N
A
A
L
A
Dog
Lupus familis
XP_549245
890
99571
S636
S
F
E
T
I
S
A
S
G
L
N
A
A
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1B1
623
69573
H395
G
P
N
G
A
I
I
H
Y
A
P
V
P
E
T
Rat
Rattus norvegicus
O54975
623
69639
H395
G
P
N
G
A
I
I
H
Y
A
P
I
P
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521654
589
66878
M361
E
P
Y
S
P
V
M
M
T
K
A
V
K
N
Q
Chicken
Gallus gallus
XP_421751
623
69997
H395
G
P
N
G
A
I
I
H
Y
K
P
V
P
E
T
Frog
Xenopus laevis
NP_001084745
621
69004
H393
G
P
N
A
A
I
I
H
Y
K
P
V
P
E
T
Zebra Danio
Brachydanio rerio
NP_957326
702
79242
S448
S
F
E
T
I
S
A
S
G
P
N
A
A
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477409
613
68487
S385
S
A
S
G
P
N
G
S
V
I
H
Y
H
P
K
Honey Bee
Apis mellifera
XP_392697
724
82990
Y441
S
F
P
T
I
A
G
Y
G
P
H
A
A
I
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07825
749
84906
Y496
R
E
A
L
I
D
E
Y
R
A
A
E
K
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
98
63.1
N.A.
40.2
39.6
N.A.
59
41
41
54.7
N.A.
39.3
36.1
N.A.
N.A.
Protein Similarity:
100
96.8
98.9
68.3
N.A.
58.6
58.1
N.A.
68.4
58.9
60.2
68.9
N.A.
57.4
54.7
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
0
0
N.A.
0
0
0
93.3
N.A.
13.3
46.6
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
0
0
N.A.
6.6
0
0
93.3
N.A.
33.3
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
31
8
31
8
0
24
16
39
47
8
31
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
31
8
0
0
8
0
0
0
0
8
0
31
0
% E
% Phe:
0
39
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
31
0
0
31
0
0
16
0
39
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
31
0
0
16
0
8
0
0
% H
% Ile:
0
0
0
0
47
39
31
0
0
8
0
8
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
24
0
0
16
0
8
% K
% Leu:
0
0
0
8
0
0
0
0
0
24
8
0
0
39
8
% L
% Met:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
31
0
0
8
0
0
0
0
31
8
0
8
0
% N
% Pro:
8
39
8
0
16
0
0
0
0
16
31
0
31
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
47
8
8
8
0
31
8
39
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
39
8
0
0
0
8
0
0
0
0
0
39
% T
% Val:
0
0
0
0
0
8
0
0
8
0
0
31
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
16
31
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _