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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPNPEP2
All Species:
13.03
Human Site:
S280
Identified Species:
23.89
UniProt:
O43895
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43895
NP_003390.4
674
75625
S280
I
R
L
F
A
N
K
S
R
F
S
S
E
T
L
Chimpanzee
Pan troglodytes
XP_521256
675
75579
S280
I
R
L
F
A
N
K
S
R
F
S
S
E
T
L
Rhesus Macaque
Macaca mulatta
XP_001091201
674
75480
S280
I
R
L
F
A
N
K
S
R
F
S
S
E
T
L
Dog
Lupus familis
XP_549245
890
99571
S494
I
R
L
F
V
N
K
S
C
L
D
S
E
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1B1
623
69573
L253
G
V
K
Q
H
L
L
L
D
L
G
L
E
A
E
Rat
Rattus norvegicus
O54975
623
69639
L253
G
V
K
Q
H
L
L
L
D
L
G
L
E
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521654
589
66878
E219
K
I
Y
H
L
S
D
E
F
T
G
S
S
W
K
Chicken
Gallus gallus
XP_421751
623
69997
L253
A
V
R
E
H
L
Q
L
D
S
T
L
E
P
E
Frog
Xenopus laevis
NP_001084745
621
69004
L251
G
F
R
E
H
L
L
L
D
S
S
P
P
P
E
Zebra Danio
Brachydanio rerio
NP_957326
702
79242
R306
W
L
F
V
H
T
E
R
I
T
E
E
L
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477409
613
68487
L243
L
F
V
D
S
G
K
L
P
T
D
F
V
Q
H
Honey Bee
Apis mellifera
XP_392697
724
82990
E299
H
K
I
L
R
S
V
E
E
H
L
K
M
D
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07825
749
84906
Y354
Y
N
P
V
F
F
S
Y
V
A
I
N
E
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
98
63.1
N.A.
40.2
39.6
N.A.
59
41
41
54.7
N.A.
39.3
36.1
N.A.
N.A.
Protein Similarity:
100
96.8
98.9
68.3
N.A.
58.6
58.1
N.A.
68.4
58.9
60.2
68.9
N.A.
57.4
54.7
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
6.6
6.6
N.A.
6.6
6.6
6.6
0
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
6.6
6.6
N.A.
13.3
20
6.6
13.3
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
24
0
0
0
0
8
0
0
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
31
0
16
0
0
16
0
% D
% Glu:
0
0
0
16
0
0
8
16
8
0
8
8
62
0
39
% E
% Phe:
0
16
8
31
8
8
0
0
8
24
0
8
0
0
8
% F
% Gly:
24
0
0
0
0
8
0
0
0
0
24
0
0
0
0
% G
% His:
8
0
0
8
39
0
0
0
0
8
0
0
0
0
8
% H
% Ile:
31
8
8
0
0
0
0
0
8
0
8
0
0
0
0
% I
% Lys:
8
8
16
0
0
0
39
0
0
0
0
8
0
8
8
% K
% Leu:
8
8
31
8
8
31
24
39
0
24
8
24
8
0
31
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
0
31
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
8
0
0
8
8
16
0
% P
% Gln:
0
0
0
16
0
0
8
0
0
0
0
0
0
8
0
% Q
% Arg:
0
31
16
0
8
0
0
8
24
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
16
8
31
0
16
31
39
8
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
24
8
0
0
31
0
% T
% Val:
0
24
8
16
8
0
8
0
8
0
0
0
8
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _