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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPNPEP2
All Species:
14.55
Human Site:
S225
Identified Species:
26.67
UniProt:
O43895
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43895
NP_003390.4
674
75625
S225
E
K
V
S
G
V
R
S
Q
M
Q
K
H
Q
K
Chimpanzee
Pan troglodytes
XP_521256
675
75579
S225
E
K
V
S
G
V
R
S
Q
M
Q
K
H
Q
K
Rhesus Macaque
Macaca mulatta
XP_001091201
674
75480
S225
E
K
V
S
G
V
R
S
Q
M
Q
K
H
Q
K
Dog
Lupus familis
XP_549245
890
99571
S439
E
K
V
S
D
I
R
S
Q
M
Q
K
H
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1B1
623
69573
V198
E
R
S
I
A
W
F
V
V
T
A
L
D
E
I
Rat
Rattus norvegicus
O54975
623
69639
V198
E
R
S
I
V
W
F
V
V
T
A
L
D
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521654
589
66878
G164
T
P
D
G
G
T
I
G
F
D
P
F
L
F
S
Chicken
Gallus gallus
XP_421751
623
69997
V198
E
R
K
V
V
W
F
V
V
T
A
L
D
E
V
Frog
Xenopus laevis
NP_001084745
621
69004
V196
E
K
K
A
S
W
I
V
L
T
G
L
D
E
V
Zebra Danio
Brachydanio rerio
NP_957326
702
79242
Q251
K
V
E
Q
I
R
A
Q
I
I
D
N
P
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477409
613
68487
Q188
K
K
W
D
V
V
R
Q
Q
L
K
E
K
N
A
Honey Bee
Apis mellifera
XP_392697
724
82990
S244
I
R
I
E
M
E
I
S
K
A
D
A
L
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07825
749
84906
E299
L
K
Y
E
F
H
G
E
E
F
K
D
K
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
98
63.1
N.A.
40.2
39.6
N.A.
59
41
41
54.7
N.A.
39.3
36.1
N.A.
N.A.
Protein Similarity:
100
96.8
98.9
68.3
N.A.
58.6
58.1
N.A.
68.4
58.9
60.2
68.9
N.A.
57.4
54.7
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
6.6
6.6
N.A.
6.6
6.6
13.3
6.6
N.A.
26.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
20
20
N.A.
6.6
20
26.6
20
N.A.
53.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
8
0
0
8
24
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
8
0
0
0
0
8
16
8
31
0
0
% D
% Glu:
62
0
8
16
0
8
0
8
8
0
0
8
0
31
8
% E
% Phe:
0
0
0
0
8
0
24
0
8
8
0
8
0
8
0
% F
% Gly:
0
0
0
8
31
0
8
8
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
31
0
0
% H
% Ile:
8
0
8
16
8
8
24
0
8
8
0
0
0
0
16
% I
% Lys:
16
54
16
0
0
0
0
0
8
0
16
31
16
8
39
% K
% Leu:
8
0
0
0
0
0
0
0
8
8
0
31
16
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
31
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
8
0
8
0
0
% P
% Gln:
0
0
0
8
0
0
0
16
39
0
31
0
0
24
0
% Q
% Arg:
0
31
0
0
0
8
39
0
0
0
0
0
0
8
0
% R
% Ser:
0
0
16
31
8
0
0
39
0
0
0
0
0
0
8
% S
% Thr:
8
0
0
0
0
8
0
0
0
31
0
0
0
0
0
% T
% Val:
0
8
31
8
24
31
0
31
24
0
0
0
0
8
16
% V
% Trp:
0
0
8
0
0
31
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _