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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPNPEP2
All Species:
12.42
Human Site:
S176
Identified Species:
22.78
UniProt:
O43895
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43895
NP_003390.4
674
75625
S176
Y
D
L
A
L
Q
G
S
N
R
Q
L
V
S
I
Chimpanzee
Pan troglodytes
XP_521256
675
75579
S176
Y
D
L
A
L
Q
G
S
N
R
Q
L
V
S
I
Rhesus Macaque
Macaca mulatta
XP_001091201
674
75480
S176
Y
N
L
A
L
Q
G
S
N
R
Q
L
V
S
I
Dog
Lupus familis
XP_549245
890
99571
S390
Y
Y
T
A
L
K
N
S
N
I
Q
L
V
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1B1
623
69573
N149
H
L
V
P
V
K
E
N
L
V
D
K
I
W
T
Rat
Rattus norvegicus
O54975
623
69639
N149
H
L
V
P
V
K
E
N
L
V
D
K
I
W
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521654
589
66878
L115
A
G
T
V
V
V
S
L
M
G
A
A
L
W
T
Chicken
Gallus gallus
XP_421751
623
69997
N149
D
L
V
P
V
K
E
N
L
I
D
T
I
W
T
Frog
Xenopus laevis
NP_001084745
621
69004
N147
H
L
V
P
V
Q
E
N
L
I
D
S
I
W
A
Zebra Danio
Brachydanio rerio
NP_957326
702
79242
A202
Y
N
T
N
L
A
P
A
D
L
I
L
K
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477409
613
68487
A139
I
E
T
E
L
S
S
A
E
C
Q
L
V
P
I
Honey Bee
Apis mellifera
XP_392697
724
82990
V195
A
N
S
S
I
R
L
V
P
V
R
N
N
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07825
749
84906
M250
D
Y
V
S
F
R
K
M
I
D
T
K
Y
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
98
63.1
N.A.
40.2
39.6
N.A.
59
41
41
54.7
N.A.
39.3
36.1
N.A.
N.A.
Protein Similarity:
100
96.8
98.9
68.3
N.A.
58.6
58.1
N.A.
68.4
58.9
60.2
68.9
N.A.
57.4
54.7
N.A.
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
0
0
N.A.
0
0
6.6
33.3
N.A.
33.3
0
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
40
40
N.A.
13.3
33.3
40
53.3
N.A.
46.6
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
31
0
8
0
16
0
0
8
8
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
16
16
0
0
0
0
0
0
8
8
31
0
0
8
0
% D
% Glu:
0
8
0
8
0
0
31
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
24
0
0
8
0
0
0
0
0
% G
% His:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
8
24
8
0
31
0
47
% I
% Lys:
0
0
0
0
0
31
8
0
0
0
0
24
8
0
0
% K
% Leu:
0
31
24
0
47
0
8
8
31
8
0
47
8
8
0
% L
% Met:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% M
% Asn:
0
24
0
8
0
0
8
31
31
0
0
8
8
0
0
% N
% Pro:
0
0
0
31
0
0
8
0
8
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
31
0
0
0
0
39
0
0
0
0
% Q
% Arg:
0
0
0
0
0
16
0
0
0
24
8
0
0
0
0
% R
% Ser:
0
0
8
16
0
8
16
31
0
0
0
8
0
39
0
% S
% Thr:
0
0
31
0
0
0
0
0
0
0
8
8
0
0
31
% T
% Val:
0
0
39
8
39
8
0
8
0
24
0
0
39
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
0
% W
% Tyr:
39
16
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _