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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AHCYL1
All Species:
40.61
Human Site:
S494
Identified Species:
68.72
UniProt:
O43865
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43865
NP_006612.2
530
58951
S494
K
M
D
E
Y
V
A
S
L
H
L
P
S
F
D
Chimpanzee
Pan troglodytes
XP_514386
716
78745
S680
K
M
D
E
Y
V
A
S
L
H
L
P
S
F
D
Rhesus Macaque
Macaca mulatta
XP_001096843
490
54232
F453
S
C
S
T
V
P
T
F
V
L
S
I
T
A
T
Dog
Lupus familis
XP_854595
483
53735
S447
K
M
D
E
Y
V
A
S
L
H
L
P
S
F
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80SW1
530
58933
S494
K
M
D
E
Y
V
A
S
L
H
L
P
S
F
D
Rat
Rattus norvegicus
P10760
432
47520
E396
K
L
D
E
A
V
A
E
A
H
L
G
K
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505334
529
59118
S494
K
M
D
E
Y
V
A
S
L
H
L
P
S
F
D
Chicken
Gallus gallus
XP_414971
545
60544
S509
K
M
D
E
Y
V
A
S
L
H
L
P
T
F
D
Frog
Xenopus laevis
P51893
433
47728
A398
L
D
E
A
V
A
A
A
H
L
D
K
L
G
V
Zebra Danio
Brachydanio rerio
NP_958450
512
56757
S476
K
M
D
E
Y
V
A
S
L
H
L
P
N
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P50245
492
54222
S456
K
M
D
E
Y
V
A
S
L
H
L
A
T
F
D
Honey Bee
Apis mellifera
XP_624152
532
58599
S496
K
M
D
E
Y
V
A
S
L
H
L
P
T
F
D
Nematode Worm
Caenorhab. elegans
P27604
437
47517
L402
L
D
E
E
V
A
Y
L
H
L
A
Q
L
G
V
Sea Urchin
Strong. purpuratus
XP_797199
538
59107
T502
K
L
D
E
Y
V
A
T
L
H
L
P
S
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
92.2
91.1
N.A.
100
43.2
N.A.
92.2
85.6
43.5
87.7
N.A.
64.5
71.9
43.7
72.8
Protein Similarity:
100
74
92.2
91.1
N.A.
100
59.4
N.A.
93.9
90.6
60.1
92.2
N.A.
78.6
81
59.2
82.3
P-Site Identity:
100
100
0
100
N.A.
100
46.6
N.A.
100
93.3
6.6
93.3
N.A.
86.6
93.3
6.6
86.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
60
N.A.
100
100
20
100
N.A.
93.3
100
13.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
15
86
8
8
0
8
8
0
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
79
0
0
0
0
0
0
0
8
0
0
0
72
% D
% Glu:
0
0
15
86
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
72
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
15
79
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
79
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% K
% Leu:
15
15
0
0
0
0
0
8
72
22
79
0
15
8
0
% L
% Met:
0
65
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
65
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
8
0
0
0
0
65
0
0
8
0
43
0
0
% S
% Thr:
0
0
0
8
0
0
8
8
0
0
0
0
29
0
8
% T
% Val:
0
0
0
0
22
79
0
0
8
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
72
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _